New research development on trans fatty acids in food: Biological effects, analytical methods, formation mechanism, and mitigating measures

Q Guo, T Li, Y Qu, M Liang, Y Ha, Y Zhang… - Progress in lipid …, 2023 - Elsevier
The trans fatty acids (TFAs) in food are mainly generated from the ruminant animals (meat
and milk) and processed oil or oil products. Excessive intake of TFAs (> 1% of total energy …

Thiyl radicals in organic synthesis

F Denes, M Pichowicz, G Povie, P Renaud - Chemical reviews, 2014 - ACS Publications
Thiyl radicals have been used by nature in a broad range of biochemical processes. For
instance, thiol residues play an important role in many enzymatic processes as illustrated by …

[HTML][HTML] Chemistry of phospholipid oxidation

A Reis, CM Spickett - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2012 - Elsevier
The oxidation of lipids has long been a topic of interest in biological and food sciences, and
the fundamental principles of non-enzymatic free radical attack on phospholipids are well …

Lipid geometrical isomerism: from chemistry to biology and diagnostics

C Chatgilialoglu, C Ferreri, M Melchiorre… - Chemical …, 2014 - ACS Publications
Lipid research in the life sciences has renewed its attractiveness in the last two decades or
so, going from chemical, analytical, and biological subjects, to making important connections …

Hexadecenoic fatty acid isomers in human blood lipids and their relevance for the interpretation of lipidomic profiles

A Sansone, E Tolika, M Louka, V Sunda, S Deplano… - PLoS …, 2016 - journals.plos.org
Monounsaturated fatty acids (MUFA) are emerging health biomarkers, and in particular the
ratio between palmitoleic acid (9 cis-16: 1) and palmitic acid (16: 0) affords the delta-9 …

Probing the role of cysteine thiyl radicals in biology: eminently dangerous, difficult to scavenge

B Moosmann, P Hajieva - Antioxidants, 2022 - mdpi.com
Thiyl radicals are exceptionally interesting reactive sulfur species (RSS), but rather rarely
considered in a biological or medical context. We here review the reactivity of protein thiyl …

Role of fatty acid-based functional lipidomics in the development of molecular diagnostic tools

C Ferreri, C Chatgilialoglu - Expert Review of Molecular …, 2012 - Taylor & Francis
Lipids are molecules with different structures which have the feature of water insolubility in
common. They have very important biological roles within structural, functional and signaling …

[BOOK][B] Membrane lipidomics for personalized health

C Ferreri, C Chatgilialoglu - 2015 - books.google.com
Lipidomics is an important aspect of personalized medicine in relation to nutrition and
metabolism. This approach has become important due to the substantial presence of …

The reaction of thiyl radical with methyl linoleate: Completing the picture

C Chatgilialoglu, C Ferreri, M Guerra… - Journal of the …, 2017 - ACS Publications
Cis lipids can be converted by thiols and free radicals into trans lipids, which are therefore a
valuable tell-tale for free radical activity in the cell's lipidome. Our previous studies have …

Hexadecenoic fatty acid isomers: a chemical biology approach for human plasma biomarker development

A Sansone, M Melchiorre… - Chemical Research …, 2013 - ACS Publications
Hexadecenoic fatty acids are monounsaturated lipid components, which are interesting
targets of plasma lipidomic studies and biomarker development. The main positional …