Filamentous fungi are unique organisms—rivaled only by actinomycetes and plants—in
producing a wide range of natural products called secondary metabolites. These …

The filamentous fungus Magnaporthe oryzae causes rice blast, the most serious disease of
cultivated rice. Cellular differentiation of M. oryzae forms an infection structure called the …

Gene replacement via homologous double crossover in filamentous fungi requires relatively
long (preferentially> 0.5 kb) flanking regions of the target gene. For this reason, gene …

Secondary metabolites, or biochemical indicators of fungal development, are of intense
interest to humankind due to their pharmaceutical and/or toxic properties. We present here a …

The formation of mitotically derived spores, called conidia, is a common reproductive mode
in filamentous fungi, particularly among the large fungal class Ascomycetes. Asexual …

Cellular differentiation, mating, and filamentous growth are regulated in many fungi by
environmental and nutritional signals. For example, in response to nitrogen limitation …

Filamentous fungi produce a number of small bioactive molecules as part of their secondary
metabolism ranging from benign antibiotics such as penicillin to threatening mycotoxins …

The genus Aspergillus represents a diverse group of fungi that are among the most
abundant fungi in the world. Germination of a spore can lead to a vegetative mycelium that …

Fungal secondary metabolites are of intense interest to humankind due to their
pharmaceutical (antibiotics) and/or toxic (mycotoxins) properties. In the past decade …

Traditional molecular techniques have been used in research in discovering the genes and
enzymes that are involved in aflatoxin formation and genetic regulation. We cloned most, if …