Two of the most prevalent neurodegenerative disorders (NDDs), Alzheimer's disease (AD)
and Parkinson's disease (PD), present significant challenges to healthcare systems …

N6-methyladenosine (m6A) regulates mRNA metabolism. While it has been implicated in
the development of the mammalian brain and in cognition, the role of m6A in synaptic …

Abstract Background Loss of the Sortilin-related receptor 1 (SORL1) gene seems to act as a
causal event for Alzheimer's disease (AD). Recent studies have established that loss of …

AMPA receptors are tetrameric ionic glutamate receptors, which mediate 90% fast excitatory
synaptic transmission induced by excitatory glutamate in the mammalian central nervous …

The localization, number, and function of postsynaptic AMPA-type glutamate receptors
(AMPARs) are crucial for synaptic plasticity, a cellular correlate for learning and memory …

Tau pathology is a hallmark of Alzheimer's disease (AD) and other tauopathies, but how
pathological tau accumulation alters the glutamate receptor dynamics driving synaptic …

Learning and memory rely on changes in postsynaptic glutamergic α-amino-3-hydroxy-5-
methyl-4-isoxazolepropionic acid (AMPA)-type receptor (AMPAR) number, spatial …

Synaptic dysfunction is an early feature in Alzheimer's disease (AD) pathogenesis and a
major morphological correlate of memory deficits. Given the main synaptic location of N …

N‐methyl‐d‐aspartate receptors (NMDARs) are pivotal players in the synaptic transmission
and synaptic plasticity underlying learning and memory. Accordingly, dysfunction of …

Alzheimer disease (AD) is a prevalent neurodegenerative disorder that affects synapses and
leads to progressive cognitive decline. The role of N-methyl-D-aspartic acid (NMDA) …