Although, drugs are required in the various skin compartments such as viable epidermis,
dermis, or hair follicles, to efficiently treat skin diseases, drug delivery into and across the …

Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

The papillary dermis of human skin is responsible for its biomechanical properties and for
supply of epidermis with chemicals. Dermis is mainly composed of structural protein …

Importance Basal cell carcinomas (BCCs) are diagnosed by clinical evaluation, which can
include dermoscopic evaluation, biopsy, and histopathologic examination. Recent …

Fluorescence lifetime imaging (FLIm) is an optical spectroscopic imaging technique capable
of real‐time assessments of tissue properties in clinical settings. Label‐free FLIm is sensitive …

Abstract Fluorescence Lifetime Imaging (FLIM) in life sciences based on ultrashort laser
scanning microscopy and time-correlated single photon counting (TCSPC) started 30 years …

Understanding the delivery and diffusion of topically-applied drugs on human skin is of
paramount importance in both pharmaceutical and cosmetics research. This information is …

High resolution multiphoton tomography and fluorescence lifetime imaging differentiates
glioma from adjacent brain in native tissue samples ex vivo. Presently, multiphoton …

This monograph focuses on modern femtosecond laser microscopes for two photon imaging
and nanoprocessing, on laser tweezers for cell micromanipulation as well as on …

This review summarizes the historical and more recent developments of multiphoton
microscopy, as applied to dermatology. Multiphoton microscopy offers several advantages …