In this overview, we summarize the findings of the literature with regards to physiology and
pathophysiology of ultra-marathon running. The number of ultra-marathon races and the …

Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …

Regular exercise has multi-system anti-aging effects. Here we summarize how exercise
impacts the major hallmarks of aging. We propose that, besides searching for novel …

Objective The main objective of this systematic review is to assess the effects of obesity on
telomere length. Methods The following databases were searched: MEDLINE, EMBASE …

Background Even before the onset of age-related diseases, obesity might be a contributing
factor to the cumulative burden of oxidative stress and chronic inflammation throughout the …

Exercise training is one of the few therapeutic interventions that improves health span by
delaying the onset of age-related diseases and preventing early death. The length of …

Background: Although telomere shortening occurs as a natural part of aging, there is now a
robust body of research that suggests that there is a relationship between psychosocial …

Aging is a risk factor for several pathologies, restricting one's health span, and promoting
chronic diseases (eg, cardiovascular and neurodegenerative diseases), as well as cancer …

Glioma, the most common central nervous system cancer in adults, has poor prognosis.
Here we identify a new SNP associated with glioma risk, rs1920116 (near TERC), that …

Study design Family members caring for chronically ill relatives are typically sedentary,
chronically stressed, and at high risk of disease. Observational reports suggest caregivers …