Key Points Frailty in Older Adults Assessing frailty enables clinicians to predict the outcomes
and risks of health conditions, target the delivery of evidence-based interventions, and tailor …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Executive summary Around the world, populations are ageing at a faster pace than in the
past and this demographic transition will have effects on all aspects of societies. In May …

Background Myocardial infarction (MI) is one of the life-threatening coronary-associated
pathologies characterized by sudden cardiac death. The provision of complete insight into …

Background falls and fall-related injuries are common in older adults, have negative effects
on functional independence and quality of life and are associated with increased morbidity …

Off-label use of medication may be presented in these guidelines if a sufficient level of
evidence shows that it can be considered medically appropriate to a given condition and if …

Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Background Whether a conservative strategy of medical therapy alone or a strategy of
medical therapy plus invasive treatment is more beneficial in older adults with non–ST …

Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …

Eight years have passed since the publication of the only guideline on cardiac rehabilitation
(CR) in Japan,“Guidelines for rehabilitation in patients with cardiovascular disease (JCS …