Apoptosis is a distinct mode of cell death that is responsible for deletion of cells in normal
tissues; it also occurs in specific pathologic contexts. Morphologically, it involves rapid …

The epidermis functions as a barrier against the environment by means of several layers of
terminally differentiated, dead keratinocytes—the cornified layer, which forms the endpoint of …

The term cell necrobiology is introduced to comprise the life processes associated with
morphological, biochemical, and molecular changes which predispose, precede, and …

I. Introduction D EATH, along with growth and differentiation, is a critical part of the life cycle
of a cell. Homeostatic control of cell number is thought to be the result of the dynamic …

Apoptosis is a form of programmed cell death serving physiologic and homeostatic
functions. However, recent evidence implicating apoptosis in the etiology and …

During post-lactational mammary gland involution, the bulk of mammary epithelium dies and
is reabsorbed. This massive cell death and tissue restructuring was found to be …

Tissue transglutaminase (TG) is a Ca2+-dependent acyltransferase with roles in cellular
differentiation, apoptosis, and other biological functions. In addition to being a transamidase …

The natural polyamines putrescine, spermidine and spermine are in multiple ways involved
in cell growth and the maintenance of cell viability. In the course of the last 15 years more …

Abstract Transglutaminase 2 (TGase 2), or tissue transglutaminase, catalyzes either ɛ-(γ-
glutamyl) lysine orN 1, N 8-(γ-glutamyl) spermidine isopeptide bonds. TGase 2 expression …

Selective troponin I (TnI) modification has been demonstrated to be in part responsible for
the contractile dysfunction observed with myocardial ischemia/reperfusion injury. We have …