Skeletal muscle quantitative nuclear magnetic resonance imaging and spectroscopy as an outcome measure for clinical trials
Recent years have seen tremendous progress towards therapy of many previously incurable
neuromuscular diseases. This new context has acted as a driving force for the development …
neuromuscular diseases. This new context has acted as a driving force for the development …
Age-dependent motor unit remodelling in human limb muscles
Voluntary control of skeletal muscle enables humans to interact with and manipulate the
environment. Lower muscle mass, weakness and poor coordination are common complaints …
environment. Lower muscle mass, weakness and poor coordination are common complaints …
Age‐related neuromuscular changes affecting human vastus lateralis
Key points Skeletal muscle size and strength decline in older age. The vastus lateralis, a
large thigh muscle, undergoes extensive neuromuscular remodelling in healthy ageing, as …
large thigh muscle, undergoes extensive neuromuscular remodelling in healthy ageing, as …
[HTML][HTML] Thigh muscles are more susceptible to age-related muscle loss when compared to lower leg and pelvic muscles
CJ Fuchs, R Kuipers, JA Rombouts, K Brouwers… - Experimental …, 2023 - Elsevier
Background A key hallmark of aging is the progressive loss of skeletal muscle mass. Due to
limitations of the various methods typically applied to assess muscle mass, only limited …
limitations of the various methods typically applied to assess muscle mass, only limited …
[HTML][HTML] Magnetic resonance imaging techniques for the quantitative analysis of skeletal muscle: state of the art
Background Magnetic resonance imaging (MRI) is the dominant 3D imaging modality to
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …
quantify muscle properties in skeletal muscle disorders, in inherited and acquired muscle …
Fat Replacement of Paraspinal Muscles with Aging in Healthy Adults.
Purpose The aims of this study were to investigate the age-related changes in fatty
replacement and cross-sectional area (CSA) of cervical, thoracic, and lumbar paraspinal …
replacement and cross-sectional area (CSA) of cervical, thoracic, and lumbar paraspinal …
The effect of ageing on fat infiltration of thigh and paraspinal muscles in men
Background Myosteatosis, skeletal muscle fat infiltration, is associated with inflammation
and fibrosis. The age-related increase of myosteatosis is an important characteristic of …
and fibrosis. The age-related increase of myosteatosis is an important characteristic of …
Properties of the vastus lateralis muscle in relation to age and physiological function in master cyclists aged 55–79 years
RD Pollock, KA O'Brien, LJ Daniels, KB Nielsen… - Aging …, 2018 - Wiley Online Library
In this study, results are reported from the analyses of vastus lateralis muscle biopsy
samples obtained from a subset (n= 90) of 125 previously phenotyped, highly active male …
samples obtained from a subset (n= 90) of 125 previously phenotyped, highly active male …
[HTML][HTML] Update on muscle imaging in myositis
It is evident that MRI, ultrasound and PET/CT have important roles in myositis. Continued
technological advancement and a quest for more sophisticated applications help drive …
technological advancement and a quest for more sophisticated applications help drive …
Ultrasound and magnetic resonance imaging as diagnostic tools for sarcopenia in immune-mediated rheumatic diseases (IMRDs)
F Salaffi, M Carotti, A Di Matteo, L Ceccarelli… - La radiologia …, 2022 - Springer
Sarcopenia is characterized by loss of muscle mass, altered muscle composition, fat and
fibrous tissue infiltration, and abnormal innervation, especially in older individuals with …
fibrous tissue infiltration, and abnormal innervation, especially in older individuals with …