Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: A review

C Proença, D Ribeiro, M Freitas… - Critical Reviews in Food …, 2022 - Taylor & Francis
Abstract Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide
and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α …

Phytochemistry and pharmacology of natural prenylated flavonoids

HW Lv, QL Wang, M Luo, MD Zhu, HM Liang… - Archives of pharmacal …, 2023 - Springer
Prenylated flavonoids are a special kind of flavonoid derivative possessing one or more
prenyl groups in the parent nucleus of the flavonoid. The presence of the prenyl side chain …

Natural products with potential hypoglycemic activity in T2DM: 2019-2023

Z Fei, Y Xu, G Zhang, Y Liu, H Li, L Chen - Phytochemistry, 2024 - Elsevier
As currently the most common metabolic disease, type 2 diabetes mellitus (T2DM) has
shown a continuous increase in the number of patients in recent decades. Most anti-T2DM …

Why natural antioxidants are readily recognized by biological systems? 3D architecture plays a role!

ZQ Liu - Food Chemistry, 2022 - Elsevier
A great deal of investigations has convincingly outlined the correlation of pathogenesis of
various fatal diseases with the damages caused by reactive oxygen species (ROS) in vivo …

Natural flavonoid α-glucosidase inhibitors from Retama raetam: Enzyme inhibition and molecular docking reveal important interactions with the enzyme active site

U Ghani, M Nur-e-Alam, M Yousaf, Z Ul-Haq… - Bioorganic …, 2019 - Elsevier
Abstract Retama raetam (Forsk.) Webb & Berthel plant has been traditionally used for the
treatment of diabetes mellitus and hypertension. Interest in the medicinal chemistry of the …

Antimicrobial Prenylated Isoflavones from the Leaves of the Amazonian Medicinal Plant Vatairea guianensis Aubl.

SS Çiçek, M Galarza Pérez… - Journal of natural …, 2022 - ACS Publications
Vatairea guianenis Aubl.(Fabaceae) is an Amazonian medicinal plant species traditionally
used for treating skin diseases. In an initial screening, a V. guianensis leaf extract and its …

Bioactive compounds from Retama raetam (Forssk.) Webb & Berthel. and their insecticidal activity against cotton pests Aphis gosspyii and Amrasca biguttula

AI Kamel, AR El-Rokh, AAM Dawidar, M Abdel-Mogib - Fitoterapia, 2024 - Elsevier
Cotton aphids, Aphis gosspyii and cotton jassids, Amrasca biguttula are destructive piercing
sucking pests to many strategic crops, especially cotton, not only in Egypt but also all over …

MCnebula analysis combined with alpha-glucosidase inhibitory screening reveals potential chemical contributors to efficacy enhancement of natural products after …

R Liu, J Dong, J Wang, Q Xu, Z Dong, L Wang… - Food Research …, 2025 - Elsevier
Natural products often show enhanced therapeutic effects after processing, largely due to
changes in their chemical profiles. However, identifying the key chemical classes and …

Epimesatines A–I, nine undescribed prenylated flavonoids with Sphk1 inhibitory activities from Epimedium sagittatum maxim

S **e, M Zeng, J Zhang, J Liu, J Wei, R Wang, M Li… - Phytochemistry, 2022 - Elsevier
Epimesatines A–I, nine undescribed prenylated flavonoids, along with ten known
analogues, were isolated from the aerial parts of Epimedium sagittatum Maxim. The …

[HTML][HTML] Epimesatines P–S: Four Undescribed Flavonoids from Epimedium sagittatum Maxim. and Their Cytotoxicity Activities

SS **e, X Yu, JK Zhang, ZY Hao, XK Zheng, WS Feng - Molecules, 2024 - mdpi.com
In this study, four previously undescribed flavonoids, named epimesatines P (1), Q (2), R (3),
and S (4), were isolated from the aerial parts of Epimedium sagittatum Maxim. Their …