Bacterial microcompartments

CA Kerfeld, C Aussignargues, J Zarzycki… - Nature Reviews …, 2018 - nature.com
Bacterial microcompartments (BMCs) are self-assembling organelles that consist of an
enzymatic core that is encapsulated by a selectively permeable protein shell. The potential …

Carbonic anhydrase inhibitors

CT Supuran - Bioorganic & medicinal chemistry letters, 2010 - Elsevier
Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread enzymes in all organisms,
catalyzing CO2 hydration to bicarbonate and protons. Their inhibition is exploited clinically …

A faster Rubisco with potential to increase photosynthesis in crops

MT Lin, A Occhialini, PJ Andralojc, MAJ Parry… - Nature, 2014 - nature.com
In photosynthetic organisms, d-ribulose-1, 5-bisphosphate carboxylase/oxygenase
(Rubisco) is the major enzyme assimilating atmospheric CO2 into the biosphere. Owing to …

[HTML][HTML] Carboxysome encapsulation of the CO2-fixing enzyme Rubisco in tobacco chloroplasts

BM Long, WY Hee, RE Sharwood, BD Rae… - Nature …, 2018 - nature.com
A long-term strategy to enhance global crop photosynthesis and yield involves the
introduction of cyanobacterial CO 2-concentrating mechanisms (CCMs) into plant …

Rubisco condensate formation by CcmM in β-carboxysome biogenesis

H Wang, X Yan, H Aigner, A Bracher, ND Nguyen… - Nature, 2019 - nature.com
Cells use compartmentalization of enzymes as a strategy to regulate metabolic pathways
and increase their efficiency. The α-and β-carboxysomes of cyanobacteria contain ribulose …

Native architecture of the Chlamydomonas chloroplast revealed by in situ cryo-electron tomography

BD Engel, M Schaffer, L Kuhn Cuellar, E Villa… - elife, 2015 - elifesciences.org
Chloroplast function is orchestrated by the organelle's intricate architecture. By combining
cryo-focused ion beam milling of vitreous Chlamydomonas cells with cryo-electron …

Identification of a carbonic anhydrase–Rubisco complex within the alpha-carboxysome

C Blikstad, EJ Dugan, TG Laughlin… - Proceedings of the …, 2023 - National Acad Sciences
Carboxysomes are proteinaceous organelles that encapsulate key enzymes of CO2 fixation—
Rubisco and carbonic anhydrase—and are the centerpiece of the bacterial CO2 …

Functions, Compositions, and Evolution of the Two Types of Carboxysomes: Polyhedral Microcompartments That Facilitate CO2 Fixation in Cyanobacteria and Some …

BD Rae, BM Long, MR Badger… - … and molecular biology …, 2013 - Am Soc Microbiol
Cyanobacteria are the globally dominant photoautotrophic lineage. Their success is
dependent on a set of adaptations collectively termed the CO2-concentrating mechanism …

Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production

T Li, Q Jiang, J Huang, CM Aitchison, F Huang… - Nature …, 2020 - nature.com
Compartmentalization is a ubiquitous building principle in cells, which permits segregation
of biological elements and reactions. The carboxysome is a specialized bacterial organelle …

Multivalent interactions between CsoS2 and Rubisco mediate α-carboxysome formation

LM Oltrogge, T Chaijarasphong, AW Chen… - Nature structural & …, 2020 - nature.com
Carboxysomes are bacterial microcompartments that function as the centerpiece of the
bacterial CO2-concentrating mechanism by facilitating high CO2 concentrations near the …