[HTML][HTML] The modulatory role of serotonin on human impulsive aggression

S da Cunha-Bang, GM Knudsen - Biological psychiatry, 2021 - Elsevier
The hypothesis of chronically low brain serotonin levels as pathophysiologically linked to
impulsive aggression has been around for several decades. Whereas the theory was initially …

Dynamic coupling of whole-brain neuronal and neurotransmitter systems

ML Kringelbach, J Cruzat, J Cabral… - Proceedings of the …, 2020 - pnas.org
Remarkable progress has come from whole-brain models linking anatomy and function.
Paradoxically, it is not clear how a neuronal dynamical system running in the fixed human …

A high-resolution in vivo atlas of the human brain's serotonin system

V Beliveau, M Ganz, L Feng, B Ozenne… - Journal of …, 2017 - jneurosci.org
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …

Whole-brain multimodal neuroimaging model using serotonin receptor maps explains non-linear functional effects of LSD

G Deco, J Cruzat, J Cabral, GM Knudsen… - Current biology, 2018 - cell.com
Understanding the underlying mechanisms of the human brain in health and disease will
require models with necessary and sufficient details to explain how function emerges from …

Effects of escitalopram on synaptic density in the healthy human brain: a randomized controlled trial

A Johansen, S Armand, P Plavén-Sigray… - Molecular …, 2023 - nature.com
Selective serotonin reuptake inhibitors (SSRIs) are widely used for treating neuropsychiatric
disorders. However, the exact mechanism of action and why effects can take several weeks …

Bridging gaps between images and data: a systematic update on imaging biobanks

M Gabelloni, L Faggioni, R Borgheresi, G Restante… - European …, 2022 - Springer
Background and objective The systematic collection of medical images combined with
imaging biomarkers and patient non-imaging data is the core concept of imaging biobanks …

Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages

RP Dörfel, JM Arenas‐Gomez, PM Fisher… - Human Brain …, 2023 - Wiley Online Library
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …

[HTML][HTML] A high-resolution in vivo atlas of the human brain's benzodiazepine binding site of GABAA receptors

M Nørgaard, V Beliveau, M Ganz, C Svarer, LH Pinborg… - Neuroimage, 2021 - Elsevier
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the human brain
and plays a key role in several brain functions and neuropsychiatric disorders such as …

Receptor-informed network control theory links LSD and psilocybin to a flattening of the brain's control energy landscape

SP Singleton, AI Luppi, RL Carhart-Harris… - Nature …, 2022 - nature.com
Psychedelics including lysergic acid diethylamide (LSD) and psilocybin temporarily alter
subjective experience through their neurochemical effects. Serotonin 2a (5-HT2a) receptor …

Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder

A Escrichs, Y Sanz Perl, PM Fisher… - Molecular …, 2024 - nature.com
Depression is a multifactorial clinical syndrome with a low pharmacological treatment
response rate. Therefore, identifying predictors of treatment response capable of providing …