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Review of pharmacotherapeutic targets in Alzheimer's disease and its management using traditional medicinal plants
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
cognitive decline, memory loss, and impaired daily functioning. While there is currently no …
cognitive decline, memory loss, and impaired daily functioning. While there is currently no …
Selenization of small molecule drugs: a new player on the board
There is an urgent need to develop safer and more effective modalities for the treatment of a
wide range of pathologies due to the increasing rates of drug resistance, undesired side …
wide range of pathologies due to the increasing rates of drug resistance, undesired side …
[HTML][HTML] Mechanistic insights into the potential role of dietary polyphenols and their nanoformulation in the management of Alzheimer's disease
Alzheimer's disease (AD) is a very common neurodegenerative disorder associated with
memory loss and a progressive decline in cognitive activity. The two major …
memory loss and a progressive decline in cognitive activity. The two major …
Cannabidiol-loaded nanocarriers and their therapeutic applications
Cannabidiol (CBD), one of the most promising constituents isolated from Cannabis sativa,
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …
exhibits diverse pharmacological actions. However, the applications of CBD are restricted …
[HTML][HTML] Photobiomodulation in Alzheimer's disease—A complementary method to state-of-the-art pharmaceutical formulations and nanomedicine?
Alzheimer's disease (AD), as a neurodegenerative disorder, usually develops slowly but
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
gradually worsens. It accounts for approximately 70% of dementia cases worldwide, and is …
Myco-synthesis of silver nanoparticles and their bioactive role against pathogenic microbes
Simple Summary The relatively high prevalence of microbial infections and the rising
resistance to traditional antibiotics are the causes of the need for revolutionary antibiotics …
resistance to traditional antibiotics are the causes of the need for revolutionary antibiotics …
[HTML][HTML] Three to tango: Inhibitory effect of quercetin and apigenin on acetylcholinesterase, amyloid-β aggregation and acetylcholinesterase-amyloid interaction
One of the pathological hallmarks of Alzheimer's disease (AD) is the formation of amyloid-β
plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the …
plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the …
Naturally inspired coumarin derivatives in Alzheimer's Disease Drug Discovery: latest advances and current challenges
R Orioli, F Belluti, S Gobbi, A Rampa, A Bisi - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
The main feature of neurodegenerative diseases, including Alzheimer's disease, is the
network of complex and not fully recognized neuronal pathways and targets involved in their …
network of complex and not fully recognized neuronal pathways and targets involved in their …
[HTML][HTML] New advances in the exploration of esterases with PET and fluorescent probes
A Gil-Rivas, B de Pascual-Teresa, I Ortín, A Ramos - Molecules, 2023 - mdpi.com
Esterases are hydrolases that catalyze the hydrolysis of esters into the corresponding acids
and alcohols. The development of fluorescent probes for detecting esterases is of great …
and alcohols. The development of fluorescent probes for detecting esterases is of great …
Multitargeted virtual screening and molecular simulation of natural product-like compounds against GSK3β, NMDA-receptor, and BACE-1 for the management of …
The complexity of Alzheimer's disease (AD) and several side effects of currently available
medication inclined us to search for a novel natural cure by targeting multiple key regulatory …
medication inclined us to search for a novel natural cure by targeting multiple key regulatory …