Pathogenesis of cerebral malaria—inflammation and cytoadherence

J Storm, AG Craig - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Despite decades of research on cerebral malaria (CM) there is still a paucity of knowledge
about what actual causes CM and why certain people develop it. Although sequestration of …

Malaria proteomics: insights into the parasite–host interactions in the pathogenic space

JM Bautista, P Marín-García, A Diez, IG Azcárate… - Journal of …, 2014 - Elsevier
Proteomics is improving malaria research by providing global information on relevant
protein sets from the parasite and the host in connection with its cellular structures and …

Expert‐level automated malaria diagnosis on routine blood films with deep neural networks

P Manescu, MJ Shaw, M Elmi… - American Journal of …, 2020 - Wiley Online Library
Over 200 million malaria cases globally lead to half a million deaths annually. Accurate
malaria diagnosis remains a challenge. Automated imaging processing approaches to …

Circulatory hepcidin is associated with the anti-inflammatory response but not with iron or anemic status in childhood malaria

F Burté, BJ Brown, AE Orimadegun… - Blood, The Journal …, 2013 - ashpublications.org
Cerebral malaria (CM) and severe malarial anemia (SMA) are the most serious life-
threatening clinical syndromes of Plasmodium falciparum infection in childhood. Therefore, it …

Data-driven malaria prevalence prediction in large densely populated urban holoendemic sub-Saharan West Africa

BJ Brown, P Manescu, AA Przybylski, F Caccioli… - Scientific Reports, 2020 - nature.com
Over 200 million malaria cases globally lead to half-million deaths annually. The
development of malaria prevalence prediction systems to support malaria care pathways …

Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria

J Bachmann, F Burté, S Pramana, I Conte… - PLoS …, 2014 - journals.plos.org
Systemic inflammation and sequestration of parasitized erythrocytes are central processes
in the pathophysiology of severe Plasmodium falciparum childhood malaria. However, it is …

The IL17F and IL17RA Genetic Variants Increase Risk of Cerebral Malaria in Two African Populations

S Marquet, I Conte, B Poudiougou, L Argiro… - Infection and …, 2016 - Am Soc Microbiol
Cerebral malaria (CM) is a neurological complication of infection with Plasmodium
falciparum that is partly caused by cytokine-mediated inflammation. It is not known whether …

Quantitative Proteomics Analysis of Plasmodium vivax Induced Alterations in Human Serum during the Acute and Convalescent Phases of Infection

S Ray, SK Patel, A Venkatesh, G Chatterjee… - Scientific reports, 2017 - nature.com
The radial distribution of Plasmodium vivax malaria burden has evoked enormous concern
among the global research community. In this study, we have investigated the serum …

Association of heme oxygenase 1 with the restoration of liver function after damage in murine malaria by Plasmodium yoelii

S Dey, S Mazumder, AA Siddiqui, MS Iqbal… - Infection and …, 2014 - Am Soc Microbiol
The liver efficiently restores function after damage induced during malarial infection once the
parasites are cleared from the blood. However, the molecular events leading to the …

Proteomic analysis of Plasmodium falciparum induced alterations in humans from different endemic regions of India to decipher malaria pathogenesis and identify …

S Ray, V Kumar, A Bhave, V Singh, NJ Gogtay… - Journal of …, 2015 - Elsevier
India significantly contributes to the global malaria burden and has the largest population in
the world at risk of malaria. This study aims to analyze alterations in the human serum …