Resveratrol and cardiovascular diseases

D Bonnefont-Rousselot - Nutrients, 2016‏ - mdpi.com
The increased incidence of cardiovascular diseases (CVDs) has stimulated research for
substances that could improve cardiovascular health. Among them, resveratrol (RES), a …

Advanced glycation end products: potential mechanism and therapeutic target in cardiovascular complications under diabetes

P Yang, J Feng, Q Peng, X Liu… - Oxidative Medicine and …, 2019‏ - Wiley Online Library
The occurrence and development of cardiovascular complications are predominantly
responsible for the increased morbidity and mortality observed in patients with diabetes …

The protease ADAM17 at the crossroads of disease: revisiting its significance in inflammation, cancer, and beyond

MI Saad, BJ Jenkins - The FEBS journal, 2024‏ - Wiley Online Library
The protease A Disintegrin And Metalloproteinase 17 (ADAM17) plays a central role in the
pathophysiology of several diseases. ADAM17 is involved in the cleavage and shedding of …

Association of triglyceride glucose-body mass index and hemoglobin glycation index with heart failure prevalence in hypertensive populations: a study across different …

R Wang, C Chen, G Xu, Z ** - Lipids in Health and Disease, 2024‏ - Springer
Abstract Background The Triglyceride glucose-body mass index (TyG-BMI) and hemoglobin
glycation index (HGI) are well-established surrogate markers for insulin resistance …

Chronic administration of the probiotic kefir improves the endothelial function in spontaneously hypertensive rats

AGF Friques, CM Arpini, IC Kalil, AL Gava… - Journal of Translational …, 2015‏ - Springer
Background The beverage obtained by fermentation of milk with kefir grains, a complex
matrix containing acid bacteria and yeasts, has been shown to have beneficial effects in …

Synergistic hypoglycemic effects of pumpkin polysaccharides and puerarin on type II diabetes mellitus mice

X Chen, L Qian, B Wang, Z Zhang, H Liu, Y Zhang… - Molecules, 2019‏ - mdpi.com
To investigate the hypoglycemic effect and potential mechanism of pumpkin
polysaccharides and puerarin on type II diabetes mellitus (T2DM) mice, mice were fed a …

[HTML][HTML] Challenges and opportunities for stem cell therapy in patients with chronic kidney disease

LTJ Hickson, A Eirin, LO Lerman - Kidney international, 2016‏ - Elsevier
Chronic kidney disease (CKD) is a global health care burden affecting billions of individuals
worldwide. The kidney has limited regenerative capacity from chronic insults, and for the …

Resveratrol reduces intracellular reactive oxygen species levels by inducing autophagy through the AMPK-mTOR pathway

J Song, Y Huang, W Zheng, J Yan, M Cheng… - Frontiers of …, 2018‏ - Springer
Oxidative stress induced by free fatty acid aggravates endothelial injury, which leads to
diabetic cardiovascular complications. Reduction of intracellular oxidative stress may …

Radiotracer imaging allows for noninvasive detection and quantification of abnormalities in angiosome foot perfusion in diabetic patients with critical limb ischemia …

JL Alvelo, X Papademetris… - Circulation …, 2018‏ - ahajournals.org
Background: Single photon emission computed tomography (SPECT)/computed
tomography (CT) imaging allows for assessment of skeletal muscle microvascular perfusion …

Enhancing endothelial colony-forming cells for treating diabetic vascular complications: Challenges and clinical prospects

Y Liu, CJ Lyons, C Ayu, T O'Brien - Frontiers in Endocrinology, 2024‏ - frontiersin.org
Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia, leading to
various vascular complications. Accumulating evidence indicates that endothelial colony …