[HTML][HTML] Recent developments in the use of peroxygenases–Exploring their high potential in selective oxyfunctionalisations

M Hobisch, D Holtmann, PG de Santos, M Alcalde… - Biotechnology …, 2021 - Elsevier
Peroxygenases are an emerging new class of enzymes allowing selective
oxyfunctionalisation reactions in a cofactor-independent way different from well-known P450 …

Hydrogen peroxide driven biocatalysis

BO Burek, S Bormann, F Hollmann, JZ Bloh… - Green …, 2019 - pubs.rsc.org
In general, hydrogen peroxide is a stable and relatively mild oxidant and it can be regarded
as the ultimate “green” reagent because water and oxygen are the only by-products …

[HTML][HTML] Peroxygenases en route to becoming dream catalysts. What are the opportunities and challenges?

Y Wang, D Lan, R Durrani, F Hollmann - Current opinion in chemical …, 2017 - Elsevier
Highlights•Peroxygenases are very promising catalysts for preparative oxyfunctionalization
chemistry.•The number of interesting applications and novel catalysts is growing …

Oxidations catalyzed by fungal peroxygenases

M Hofrichter, R Ullrich - Current opinion in chemical biology, 2014 - Elsevier
Highlights•Selective oxyfunctionalizations are among the most challenging reactions in
organic synthesis.•Unspecific peroxygenases (UPO) are a diverse group of secreted fungal …

Structural and Biochemical Studies Enlighten the Unspecific Peroxygenase from Hypoxylon sp. EC38 as an Efficient Oxidative Biocatalyst

L Rotilio, A Swoboda, K Ebner, C Rinnofner… - ACS …, 2021 - ACS Publications
Unspecific peroxygenases (UPOs) are glycosylated fungal enzymes that can selectively
oxidize C–H bonds. UPOs employ hydrogen peroxide as the oxygen donor and reductant …

Directed evolution of unspecific peroxygenase from Agrocybe aegerita

P Molina-Espeja, E Garcia-Ruiz… - Applied and …, 2014 - Am Soc Microbiol
Unspecific peroxygenase (UPO) represents a new type of heme-thiolate enzyme with self-
sufficient mono (per) oxygenase activity and many potential applications in organic …

Engineering a highly regioselective fungal peroxygenase for the synthesis of hydroxy fatty acids

P Gomez de Santos, A González‐Benjumea… - Angewandte …, 2023 - Wiley Online Library
The hydroxylation of fatty acids is an appealing reaction in synthetic chemistry, although the
lack of selective catalysts hampers its industrial implementation. In this study, we have …

Evolution of novel wood decay mechanisms in Agaricales revealed by the genome sequences of Fistulina hepatica and Cylindrobasidium torrendii

D Floudas, BW Held, R Riley, LG Nagy… - Fungal Genetics and …, 2015 - Elsevier
Wood decay mechanisms in Agaricomycotina have been traditionally separated in two
categories termed white and brown rot. Recently the accuracy of such a dichotomy has been …

5‐hydroxymethylfurfural conversion by fungal aryl‐alcohol oxidase and unspecific peroxygenase

J Carro, P Ferreira, L Rodríguez, A Prieto… - The FEBS …, 2015 - Wiley Online Library
Oxidative conversion of 5‐hydroxymethylfurfural (HMF) is of biotechnological interest for the
production of renewable (lignocellulose‐based) platform chemicals, such as 2, 5 …

[書籍][B] Monooxygenase, peroxidase and peroxygenase properties and reaction mechanisms of cytochrome P450 enzymes

EG Hrycay, SM Bandiera - 2015 - Springer
This review examines the monooxygenase, peroxidase and peroxygenase properties and
reaction mechanisms of cytochrome P450 (CYP) enzymes in bacterial, archaeal and …