Endolysins are enzymes used by bacteriophages at the end of their replication cycle to
degrade the peptidoglycan of the bacterial host from within, resulting in cell lysis and release …

Staphylococcus aureus is one of the most common pathogens of humans and animals,
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …

Peptidoglycan (PG) is the major structural component of the bacterial cell wall. Bacteria have
autolytic PG hydrolases that allow the cell to grow and divide. A well-studied group of PG …

Endolysins (or lysins) are highly evolved enzymes produced by bacteriophage (phage for
short) to digest the bacterial cell wall for phage progeny release. In Gram-positive bacteria …

Lysins are highly evolved enzymes produced by bacteriophage (phage for short) to digest
the bacterial cell wall for phage progeny release. In Gram-positive bacteria, small quantities …

Endolysins are phage-encoded enzymes that break down bacterial peptidoglycan at the
terminal stage of the phage reproduction cycle. Their action is tightly regulated by holins, by …

Bacteriophage lytic enzymes, or lysins, are highly evolved molecules produced by bacterial
viruses (bacteriophage) to digest the bacterial cell wall for bacteriophage progeny release …

Endolysins are double-stranded DNA bacteriophage-encoded peptidoglycan hydrolases
produced in phage-infected bacterial cells toward the end of the lytic cycle. They reach the …

The enzymatic hydrolysis of the glycosidic bond continues to gain importance, reflecting the
critically important roles complex glycans play in health and disease as well as the rekindled …

Antibiotics have saved millions of lives. However, the overuse and misuse of antibiotics have
contributed to a rapid emergence of antibiotic resistance worldwide. In addition, there is an …