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Therapeutic potential of natural compounds in Subarachnoid Haemorrhage
J Tan, H Zhu, Y Zeng, J Li, Y Zhao, M Li - Neuroscience, 2024 - Elsevier
Subarachnoid hemorrhage (SAH) is a common and fatal cerebrovascular disease with high
morbidity, mortality and very poor prognosis worldwide. SAH can induce a complex series of …
morbidity, mortality and very poor prognosis worldwide. SAH can induce a complex series of …
Sirtuins as potential targets for neuroprotection: mechanisms of early brain injury induced by subarachnoid hemorrhage
K Lei, R Wu, J Wang, X Lei, E Zhou, R Fan… - Translational Stroke …, 2024 - Springer
Subarachnoid hemorrhage (SAH) is a prevalent cerebrovascular disease with significant
global mortality and morbidity rates. Despite advancements in pharmacological and surgical …
global mortality and morbidity rates. Despite advancements in pharmacological and surgical …
Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid …
D **a, J Yuan, D Wu, H Dai, Z Zhuang - Frontiers in Immunology, 2023 - frontiersin.org
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …
Semaglutide alleviates early brain injury following subarachnoid hemorrhage by suppressing ferroptosis and neuroinflammation via SIRT1 pathway
L Chen, H Xu, C Zhang, J He… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives: Subarachnoid hemorrhage (SAH) is a major cause of incapacity and death,
imposing a significant economic burden globally. Additionally, SAH is the third most …
imposing a significant economic burden globally. Additionally, SAH is the third most …
New insights into the relationship of mitochondrial metabolism and atherosclerosis
Z Wang, W Sun, K Zhang, X Ke, Z Wang - Cellular Signalling, 2024 - Elsevier
Atherosclerotic cardiovascular and cerebrovascular diseases are the number one killer of
human health. In view of the important role of mitochondria in the formation and evolution of …
human health. In view of the important role of mitochondria in the formation and evolution of …
Development and Validation of a Prechiasmatic Mouse Model of Subarachnoid Hemorrhage to Measure Long‐Term Cognitive Deficits
D Diwan, J Mehla, JW Nelson, JD Quirk… - Advanced …, 2024 - Wiley Online Library
Controllable and reproducible animal models of aneurysmal subarachnoid hemorrhage
(SAH) are crucial for the systematic study of the pathophysiology and treatment of this …
(SAH) are crucial for the systematic study of the pathophysiology and treatment of this …
Controlling the familywise error rate in widefield optical neuroimaging of functional connectivity in mice
Significance Statistical inference in functional neuroimaging is complicated by the multiple
testing problem and spatial autocorrelation. Common methods in functional magnetic …
testing problem and spatial autocorrelation. Common methods in functional magnetic …
Pterostilbene Attenuates Subarachnoid Hemorrhage‐Induced Brain Injury through the SIRT1‐Dependent Nrf2 Signaling Pathway
Z Zhang, J Fang, J Zhou, F Ding, G Zhou… - Oxidative medicine …, 2022 - Wiley Online Library
Neuroinflammatory injury, oxidative insults, and neuronal apoptosis are major causes of
poor outcomes after subarachnoid hemorrhage (SAH). Pterostilbene (PTE), an analog of …
poor outcomes after subarachnoid hemorrhage (SAH). Pterostilbene (PTE), an analog of …
Sirt1 activation promotes long-term functional recovery after subarachnoid hemorrhage in rats
Background An increase in sirtuin 1 (SIRT1) reportedly attenuates early brain injury, delayed
cerebral ischemia, and short-term neurologic deficits in rodent models of subarachnoid …
cerebral ischemia, and short-term neurologic deficits in rodent models of subarachnoid …
Conditioning-based therapeutics for aneurysmal subarachnoid hemorrhage–A critical review
Aneurysmal subarachnoid hemorrhage (SAH) carries significant mortality and morbidity,
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …