Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Engineering therapeutical extracellular vesicles for clinical translation

Y Ma, S Dong, AJ Grippin, L Teng, AS Lee… - Trends in …, 2024 - cell.com
Cell-based therapies are revolutionizing medicine by replacing or modifying dysfunctional
cells with healthy cells or engineered derivatives, offering disease reversal and cure. One …

Exosomes as smart drug delivery vehicles for cancer immunotherapy

H Zhang, S Wang, M Sun, Y Cui, J **ng… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …

[HTML][HTML] Nanocarriers for pancreatic cancer imaging, treatments, and immunotherapies

L Liu, PG Kshirsagar, SK Gautam, M Gulati, EI Wafa… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Photodynamic-based combinatorial cancer therapy strategies: Tuning the properties of nanoplatform according to oncotherapy needs

C Chen, C Wu, J Yu, X Zhu, Y Wu, J Liu… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the wide application of photodynamic therapy (PDT) in the field of
biomedicine has proved its significance in cancer treatment. A variety of nanomaterials are …

Advances and prospects in the treatment of pancreatic cancer

H Duan, L Li, S He - International journal of nanomedicine, 2023 - Taylor & Francis
Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Ultrasound nanotheranostics: Toward precision medicine

Y Qin, X Geng, Y Sun, Y Zhao, W Chai, X Wang… - Journal of Controlled …, 2023 - Elsevier
Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Recent advances in extracellular vesicle-based organic nanotherapeutic drugs for precision cancer therapy

VN Nguyen, TNT Dao, M Cho, H Jeong… - Coordination Chemistry …, 2023 - Elsevier
Due to the critical limitations of conventional antitumor agents, great efforts have been made
to develop advanced drug delivery systems to enhance the therapeutic outcomes of …