Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in Cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

[HTML][HTML] Extracellular vesicles in nanomedicine and regenerative medicine: a review over the last decade

S Moghassemi, A Dadashzadeh, MJ Sousa, H Vlieghe… - Bioactive materials, 2024 - Elsevier
Small extracellular vesicles (sEVs) are known to be secreted by a vast majority of cells.
These sEVs, specifically exosomes, induce specific cell-to-cell interactions and can activate …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Exosomes as smart drug delivery vehicles for cancer immunotherapy

H Zhang, S Wang, M Sun, Y Cui, J **ng… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …

Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives

S Sen, J Xavier, N Kumar, MZ Ahmad, OP Ranjan - 3 Biotech, 2023 - Springer
Abstract Exosomes are nanosized (size~ 30–150 nm) natural vesicular structures released
from cells by physiological processes or pathological circumstances. Exosomes are growing …

Engineering therapeutical extracellular vesicles for clinical translation

Y Ma, S Dong, AJ Grippin, L Teng, AS Lee… - Trends in …, 2024 - cell.com
Cell-based therapies are revolutionizing medicine by replacing or modifying dysfunctional
cells with healthy cells or engineered derivatives, offering disease reversal and cure. One …

Advances and prospects in the treatment of pancreatic cancer

H Duan, L Li, S He - International journal of nanomedicine, 2023 - Taylor & Francis
Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Photodynamic-based combinatorial cancer therapy strategies: Tuning the properties of nanoplatform according to oncotherapy needs

C Chen, C Wu, J Yu, X Zhu, Y Wu, J Liu… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the wide application of photodynamic therapy (PDT) in the field of
biomedicine has proved its significance in cancer treatment. A variety of nanomaterials are …

Tumor immune escape: extracellular vesicles roles and therapeutics application

M Ahmadi, R Abbasi, J Rezaie - Cell Communication and Signaling, 2024 - Springer
Background Immune escape, a process by which tumor cells evade immune surveillance,
remains a challenge for cancer therapy. Tumor cells produce extracellular vesicles (EVs) …