The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

The wavelength-ratiometric techniques demonstrate strong advantages in fluorescence
sensing and imaging over techniques employing variations of intensity at single wavelength …

A new approach for synthesizing polycyclic heterofused 7-deazapurine heterocycles and the
corresponding nucleosides was developed based on C–H functionalization of diverse …

Interactions between DNA aptamers and protein targets hold promise for the development of
pharmaceuticals and diagnostics. As such, the utilization of fluorescent nucleobase …

Application of fluorescence techniques to investigate molecular interactions with nucleic
acids is complicated by their poor emission, making the substitution of natural nucleobases …

Fluorescent base analogues (FBAs) are versatile nucleic acid labels that can replace a
native nucleobase, while maintaining base pairing and secondary structure. Following the …

A new emissive guanosine analog CF3thG, constructed by a single trifluoromethylation step
from the previously reported thG, displays red-shifted absorption and emission spectra …

The LutR protein represses the transcription of genes encoding enzymes for the utilization of
L-lactate in Bacillus subtilis through binding to a specific DNA region. In this study, we …

Abstract Four targeting fluorescent 2-(N, N-dimethyl/diphenyl-aminophenyl)-5-substituted-
benzothiazole conjugates 3a, 3b, 6a and 6b were synthesized. Insight into the photophysical …

Characterized by their high structural similarity to their native counterparts, yet endowed with
useful photophysical features, isomorphic fluorescent nucleosides present enormous …