Heat shock protein 90 inhibitors: an update on achievements, challenges, and future directions
L Li, L Wang, QD You, XL Xu - Journal of medicinal chemistry, 2019 - ACS Publications
Hsp90 is one of the most important chaperones involved in regulating the maturation of
more than 300 client proteins, many of which are closely associated with refractory diseases …
more than 300 client proteins, many of which are closely associated with refractory diseases …
Medicinal Profile, Phytochemistry, and Pharmacological Activities of Murraya koenigii and Its Primary Bioactive Compounds
The discovery of several revitalizing molecules that can stop or reduce the pathology of a
wide range of diseases will be considered a major breakthrough of the present time …
wide range of diseases will be considered a major breakthrough of the present time …
Non-apoptotic cell death in malignant tumor cells and natural compounds
J Ye, R Zhang, F Wu, L Zhai, K Wang, M ** new strategies of diagnosis and treatment to this disease, such …
Molecules targeting the androgen receptor (AR) signaling axis beyond the AR‐Ligand binding domain
NGRD Elshan, MB Rettig… - Medicinal research reviews, 2019 - Wiley Online Library
Prostate cancer (PCa) is the second most common cause of cancer‐related mortality in men
in the United States. The androgen receptor (AR) and the physiological pathways it …
in the United States. The androgen receptor (AR) and the physiological pathways it …
Targeting reactive oxygen species in development and progression of pancreatic cancer
N Durand, P Storz - Expert review of anticancer therapy, 2017 - Taylor & Francis
Introduction: Pancreatic ductal adenocarcinoma (PDA) is characterized by expression of
oncogenic KRas which drives all aspects of tumorigenesis. Oncogenic KRas induces the …
oncogenic KRas which drives all aspects of tumorigenesis. Oncogenic KRas induces the …
The anticancer activity of carbazole alkaloids
F Song, D Liu, X Huo, D Qiu - Archiv der Pharmazie, 2022 - Wiley Online Library
Chemotherapy is the first choice for the majority of cancers, but severe side effects and drug
resistance restrict the actual clinical efficacy. Carbazole alkaloids, mainly from the Rutaceae …
resistance restrict the actual clinical efficacy. Carbazole alkaloids, mainly from the Rutaceae …