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Bioactivities and structure–activity relationships of fusidic acid derivatives: a review
J Long, W Ji, D Zhang, Y Zhu, Y Bi - Frontiers in pharmacology, 2021 - frontiersin.org
Fusidic acid (FA) is a natural tetracyclic triterpene isolated from fungi, which is clinically used
for systemic and local staphylococcal infections, including methicillin-resistant …
for systemic and local staphylococcal infections, including methicillin-resistant …
Research, development and pharmacological activity of fusidic acid and its derivatives
X Huang, QK Shen, HY Guo, ZS Quan, X Li - Journal of Molecular Structure, 2023 - Elsevier
Fusidic acid is a tetracyclic triterpenoid isolated from fungi. Fusidic acid has a wide range of
pharmacological activities, including anti-inflammatory, antimalarial, antiparasitic and …
pharmacological activities, including anti-inflammatory, antimalarial, antiparasitic and …
Synthesis of fusidic acid derivatives yields a potent antibiotic with an improved resistance profile
M Garcia Chavez, A Garcia, HY Lee… - ACS infectious …, 2021 - ACS Publications
Fusidic acid (FA) is a potent steroidal antibiotic that has been used in Europe for more than
60 years to treat a variety of infections caused by Gram-positive pathogens. Despite its …
60 years to treat a variety of infections caused by Gram-positive pathogens. Despite its …
[PDF][PDF] An efficient synthesis and antimicrobial evaluation of 5-alkenyl-and 5-styryl-1, 2, 4-oxadiazoles
M Tarasenko, V Sidneva, A Belova… - Arkivoc, 2018 - pdfs.semanticscholar.org
The cyclodehydration of O-acylamidoximes at room temperature in the superbase system
KOH/DMSO represents a simple and efficient way to 5-alkenyl-and 5-styryl-1, 2, 4 …
KOH/DMSO represents a simple and efficient way to 5-alkenyl-and 5-styryl-1, 2, 4 …
An epigrammatic status of the 'azole'-based antimalarial drugs
M Sharma, P Prasher - RSC Medicinal Chemistry, 2020 - pubs.rsc.org
The development of multidrug resistance in the malarial parasite has sabotaged majority of
the eradication efforts by restraining the inhibition profile of first line as well as second line …
the eradication efforts by restraining the inhibition profile of first line as well as second line …
[HTML][HTML] Synthesis and biological evaluation of novel fusidic acid derivatives as two-in-one agent with potent antibacterial and anti-inflammatory activity
B Tu, N Cao, B Zhang, W Zheng, J Li, X Tang, K Su, J Li… - Antibiotics, 2022 - mdpi.com
Fusidic acid (FA), a narrow-spectrum antibiotics, is highly sensitive to various Gram-positive
cocci associated with skin infections. It has outstanding antibacterial effects against certain …
cocci associated with skin infections. It has outstanding antibacterial effects against certain …
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents
A series of novel fusidic acid (FA) derivatives was synthesized by replacing the carboxylic
acid group with various ester and amide groups and evaluated in vitro for their …
acid group with various ester and amide groups and evaluated in vitro for their …
Rv0684/fusA1, an Essential Gene, Is the Target of Fusidic Acid and Its Derivatives in Mycobacterium tuberculosis
V Singh, GA Dziwornu, A Mabhula… - ACS infectious …, 2021 - ACS Publications
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a major global health concern
given the increase in multiple forms of drug-resistant TB. This underscores the importance of …
given the increase in multiple forms of drug-resistant TB. This underscores the importance of …
Implementation of simulated annealing-support vector machine on QSAR study of fusidic acid derivatives as anti-malarial agent
F Rahman, KM Lhaksmana… - 2020 6th International …, 2020 - ieeexplore.ieee.org
Malaria is a disease caused by the Plasmodium falciparum parasite and leads to many
cases of deaths. Recently, the combination of several drugs has been used to treat this …
cases of deaths. Recently, the combination of several drugs has been used to treat this …
Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity
K Singh, G Kaur, PS Shanika, GA Dziwornu… - Bioorganic & Medicinal …, 2020 - Elsevier
Fusidic acid (FA) is a potent congener of the fusidane triterpenoid class of antibiotics.
Structure-activity relationship (SAR) studies suggest the chemical structure of FA is optimal …
Structure-activity relationship (SAR) studies suggest the chemical structure of FA is optimal …