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Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
Concise review: MSC-derived exosomes for cell-free therapy
Mesenchymal stem cell transplantation is undergoing extensive evaluation as a cellular
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
therapy in human clinical trials. Because MSCs are easily isolated and amenable to culture …
Mesenchymal stromal cell homing: mechanisms and strategies for improvement
Mesenchymal stromal cells (MSCs) have been widely investigated for their therapeutic
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
potential in regenerative medicine, owing to their ability to home damaged tissue and serve …
Cell-based drug delivery systems and their in vivo fate
Cell-based drug delivery systems (DDSs) have received attention recently because of their
unique biological properties and self-powered functions, such as excellent biocompatibility …
unique biological properties and self-powered functions, such as excellent biocompatibility …
Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells
Mesenchymal stem or stromal cells (MSC) are under investigation as a potential
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …
application in a rational manner depends on reliable, clinically applicable methods for …
Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …
numerous clinical indications, including cancer, has significant promise. However, a …
Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
E Eggenhofer, V Benseler, A Kroemer… - Frontiers in …, 2012 - frontiersin.org
Mesenchymal stem cells (MSC) are under investigation as a therapy for a variety of
disorders. Although animal models show long term regenerative and immunomodulatory …
disorders. Although animal models show long term regenerative and immunomodulatory …
Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells
J Leibacher, R Henschler - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem/stromal cells (MSCs) are increasingly used as an intravenously applied
cellular therapeutic. They were found to be potent in situations such as tissue repair or …
cellular therapeutic. They were found to be potent in situations such as tissue repair or …
The life and fate of mesenchymal stem cells
E Eggenhofer, F Luk, MH Dahlke… - Frontiers in …, 2014 - frontiersin.org
Mesenchymal stem cells (MSC) are present throughout the body and are thought to play a
role in tissue regeneration and control of inflammation. MSC can be easily expanded in vitro …
role in tissue regeneration and control of inflammation. MSC can be easily expanded in vitro …