Innate immunity in diabetic kidney disease

SCW Tang, WH Yiu - Nature Reviews Nephrology, 2020 - nature.com
Increasing evidence suggests that renal inflammation contributes to the pathogenesis and
progression of diabetic kidney disease (DKD) and that anti-inflammatory therapies might …

A comprehensive SARS-CoV-2 and COVID-19 review, Part 1: Intracellular overdrive for SARS-CoV-2 infection

DA Jamison Jr, S Anand Narayanan… - European Journal of …, 2022 - nature.com
COVID-19, the disease caused by SARS-CoV-2, has claimed approximately 5 million lives
and 257 million cases reported globally. This virus and disease have significantly affected …

[PDF][PDF] Inflammatory pathways in female reproductive health and disease

HN Jabbour, KJ Sales, RD Catalano, JE Norman - Reproduction, 2009 - Citeseer
Inflammation involves alterations to vascular and immune cell function. It is well recognised
that many physiological reproductive events such as ovulation, menstruation, implantation …

[HTML][HTML] Role of the renin–angiotensin–aldosterone and kinin–kallikrein systems in the cardiovascular complications of COVID-19 and long COVID

SL Cooper, E Boyle, SR Jefferson, CRA Heslop… - International Journal of …, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus responsible
for the COVID-19 pandemic. Patients may present as asymptomatic or demonstrate mild to …

[PDF][PDF] Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment

CTT Wong, DK Rowlands, CH Wong… - Angewandte Chemie …, 2012 - academia.edu
Chronic pain is a universal health issue associated with numerous medical conditions, for
example after severe burns or following major surgery.[1] Compelling evidence suggests …

Immune system: Part I. Fundamentals of innate immunity with emphasis on molecular and cellular mechanisms of inflammatory response

WM Cruvinel, D Mesquita Júnior, JAP Araújo… - Revista brasileira de …, 2010 - SciELO Brasil
The immune system consists of an intricate network of organs, cells, and molecules
responsible for maintaining the body's homeostasis and responding to aggression in …

Novel contact–kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke

Z Zhang, C Shen, M Fang, Y Han, C Long… - Cellular and Molecular …, 2022 - Springer
Ischemic stroke is a leading cause of death and disability worldwide. Increasing evidence
indicates that ischemic stroke is a thromboinflammatory disease in which the contact–kinin …

Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw

R Medeiros, GF Passos, CE Vitor… - British journal of …, 2007 - Wiley Online Library
Background and purpose: α‐Humulene and trans‐caryophyllene are sesquiterpene
compounds identified in the essential oil of Cordia verbenacea which display topical and …

TRPA1 antagonists as potential analgesic drugs

EL Andrade, FC Meotti, JB Calixto - Pharmacology & therapeutics, 2012 - Elsevier
The necessity of safe and effective treatments for chronic pain has intensified the search for
new analgesic drugs. In the last few years, members of a closely-related family of ion …

Ubiquitin ligases at the heart of skeletal muscle atrophy control

D Peris-Moreno, L Cussonneau, L Combaret, C Polge… - Molecules, 2021 - mdpi.com
Skeletal muscle loss is a detrimental side-effect of numerous chronic diseases that
dramatically increases mortality and morbidity. The alteration of protein homeostasis is …