Nasopharyngeal carcinoma: an evolving paradigm
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …
Management of nasopharyngeal carcinoma: current practice and future perspective
Nasopharyngeal carcinoma of the undifferentiated subtype is endemic to southern China,
and patient prognosis has improved significantly over the past three decades because of …
and patient prognosis has improved significantly over the past three decades because of …
Nasopharyngeal carcinoma: ESMO-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
P Bossi, AT Chan, L Licitra, A Trama… - Annals of …, 2021 - annalsofoncology.org
Nasopharyngeal carcinoma (NPC) is a disease with unique epidemiological features. The
distribution of the disease demonstrates a clear regional, racial and gender prevalence. In …
distribution of the disease demonstrates a clear regional, racial and gender prevalence. In …
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
SA Rosenberg, JC Yang, RM Sherry, US Kammula… - Clinical cancer …, 2011 - AACR
Purpose: Most treatments for patients with metastatic melanoma have a low rate of complete
regression and thus overall survival in these patients is poor. We investigated the ability of …
regression and thus overall survival in these patients is poor. We investigated the ability of …
Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins
Purpose Tumor cells from approximately 40% of patients with Hodgkin or non-Hodgkin
lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane …
lymphoma express the type II latency Epstein-Barr virus (EBV) antigens latent membrane …
The role of Epstein–Barr virus in nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …
Improving chimeric antigen receptor-modified T cell function by reversing the immunosuppressive tumor microenvironment of pancreatic cancer
The adoptive transfer of T cells redirected to tumor-associated antigens via transgenic
expression of chimeric antigen receptors (CARs) has produced tumor responses, even in …
expression of chimeric antigen receptors (CARs) has produced tumor responses, even in …
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
SA Rosenberg, NP Restifo, JC Yang… - Nature Reviews …, 2008 - nature.com
Adoptive cell therapy (ACT) using autologous tumour-infiltrating lymphocytes has emerged
as the most effective treatment for patients with metastatic melanoma and can mediate …
as the most effective treatment for patients with metastatic melanoma and can mediate …
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
Cytotoxic T lymphocytes (CTLs) directed to nonviral tumor–associated antigens do not
survive long term and have limited antitumor activity in vivo, in part because such tumor cells …
survive long term and have limited antitumor activity in vivo, in part because such tumor cells …
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
T-cell immunotherapy that takes advantage of Epstein-Barr virus (EBV)–stimulated immunity
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …
has the potential to fill an important niche in targeted therapy for EBV-related cancers. To …