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Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity
K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …
claiming millions of lives and pushing healthcare systems in many countries to the brink …
Genetic polymorphisms of ACE1, ACE2, IFTM3, TMPRSS2 and TNFα genes associated with susceptibility and severity of SARS-CoV-2 infection: a systematic review …
V Pecoraro, M Cuccorese, T Trenti - Clinical and Experimental Medicine, 2023 - Springer
Background Some human polymorphisms of ACE1, ACE2, IFITM3, TMPRSS2 and TNFα
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …
Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease
M Sabater Molina, E Nicolás Rocamora, AI Bendicho… - PloS one, 2022 - journals.plos.org
Background Infection by the SARS-Cov-2 virus produces in humans a disease of highly
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
variable and unpredictable severity. The presence of frequent genetic single nucleotide …
Network analysis-guided drug repurposing strategies targeting LPAR receptor in the interplay of COVID, Alzheimer's, and diabetes
The COVID-19 pandemic caused by the SARS-CoV-2 virus has greatly affected global
health. Emerging evidence suggests a complex interplay between Alzheimer's disease (AD) …
health. Emerging evidence suggests a complex interplay between Alzheimer's disease (AD) …
Potential genes associated with COVID-19 and comorbidity
S Feng, F Song, W Guo, J Tan, X Zhang… - … journal of medical …, 2022 - pmc.ncbi.nlm.nih.gov
Hypertension, diabetes mellitus, and coronary artery disease are common comorbidities and
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
dangerous factors for infection and serious COVID-19. Polymorphisms in genes associated …
The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …
identified as candidates for genetic association studies on COVID-19 severity. Published …
Molecular signature of postmortem lung tissue from COVID-19 patients suggests distinct trajectories driving mortality
To elucidate the molecular mechanisms that manifest lung abnormalities during severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, we performed whole …
Global distribution of ACE1 (rs4646994) and ACE2 (rs2285666) polymorphisms associated with COVID-19: A systematic review and meta-analysis
Background Recent studies emphasize the significant impact of the renin-angiotensin
aldosterone system (RAAS) as a risk factor associated with severe acute respiratory …
aldosterone system (RAAS) as a risk factor associated with severe acute respiratory …
SARS-CoV-2 infection of endothelial cells, dependent on flow-induced ACE2 expression, drives hypercytokinemia in a vascularized microphysiological system
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible
for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by …
for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by …
Relationship between angiotensin-converting enzyme insertion/deletion polymorphism and the risk of COVID-19: a meta-analysis
H Luoyi, P Yan, F Qihong - Journal of the Renin-Angiotensin …, 2023 - journals.sagepub.com
Introduction. Research shows the correlation between angiotensin-converting enzyme
(ACE) deletion and insertion (D/I) polymorphism and COVID-19 risk; yet, conclusive …
(ACE) deletion and insertion (D/I) polymorphism and COVID-19 risk; yet, conclusive …