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[HTML][HTML] Factors affecting the performance of HRP2-based malaria rapid diagnostic tests
The recent COVID-19 pandemic has profoundly impacted global malaria elimination
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
programs, resulting in a sharp increase in malaria morbidity and mortality. To reduce this …
The laboratory diagnosis of malaria: a focus on the diagnostic assays in non-endemic areas
A Calderaro, G Piccolo, C Chezzi - International Journal of Molecular …, 2024 - mdpi.com
Even if malaria is rare in Europe, it is a medical emergency and programs for its control
should ensure both an early diagnosis and a prompt treatment within 24–48 h from the onset …
should ensure both an early diagnosis and a prompt treatment within 24–48 h from the onset …
Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia
SM Feleke, EN Reichert, H Mohammed… - Nature …, 2021 - nature.com
In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
Smartphone-based DNA diagnostics for malaria detection using deep learning for local decision support and blockchain technology for security
In infectious disease diagnosis, results need to be communicated rapidly to healthcare
professionals once testing has been completed so that care pathways can be implemented …
professionals once testing has been completed so that care pathways can be implemented …
High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion ty** by digital PCR to monitor malaria rapid diagnostic test efficacy
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false …
Flexible and cost-effective genomic surveillance of P. falciparum malaria with targeted nanopore sequencing
M de Cesare, M Mwenda, AE Jeffreys, J Chirwa… - Nature …, 2024 - nature.com
Genomic surveillance of Plasmodium falciparum malaria can provide policy-relevant
information about antimalarial drug resistance, diagnostic test failure, and the evolution of …
information about antimalarial drug resistance, diagnostic test failure, and the evolution of …
Detection of high prevalence of Plasmodium falciparum histidine-rich protein 2/3 gene deletions in Assosa zone, Ethiopia: implication for malaria diagnosis
GS Alemayehu, K Blackburn, K Lopez… - Malaria journal, 2021 - Springer
Abstract Background Rapid diagnostic tests (RDTs) targeting histidine rich protein 2 (HRP2)
are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the …
are widely used for diagnosis of Plasmodium falciparum infections. Besides PfHRP2, the …
Widespread pfhrp2/3 deletions and HRP2-based false-negative results in southern Ethiopia
B Mekonen, S Dugassa, SM Feleke, B Dufera, B Gidisa… - Malaria Journal, 2024 - Springer
Abstract Background Rapid diagnostic tests (RDTs) play a significant role in expanding case
management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen …
management in peripheral healthcare systems. Histidine-rich protein-2 (HRP2) antigen …
Analysis of false-negative rapid diagnostic tests for symptomatic malaria in the Democratic Republic of the Congo
The majority of Plasmodium falciparum malaria diagnoses in Africa are made using rapid
diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing reports of false …
diagnostic tests (RDTs) that detect histidine-rich protein 2. Increasing reports of false …
Expansion of artemisinin partial resistance mutations and lack of histidine rich protein-2 and -3 deletions in Plasmodium falciparum infections from Rukara, Rwanda
Background Emerging artemisinin partial resistance and diagnostic resistance are a threat
to malaria control in Africa. Plasmodium falciparum kelch13 (k13) propeller-domain …
to malaria control in Africa. Plasmodium falciparum kelch13 (k13) propeller-domain …