Organismal life encounters reactive oxidants from internal metabolism and environmental
toxicant exposure. Reactive oxygen and nitrogen species cause oxidative stress and are …

Interest in the topic of tumour metabolism has waxed and waned over the past century of
cancer research. The early observations of Warburg and his contemporaries established …

Parkinson's disease prevalence is rapidly increasing in an aging global population. With this
increase comes exponentially rising social and economic costs, emphasizing the immediate …

Many lines of evidence suggest that mitochondria have a central role in ageing-related
neurodegenerative diseases. Mitochondria are critical regulators of cell death, a key feature …

Oxidative stress plays an important role in the degeneration of dopaminergic neurons in
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …

Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder, characterized by motor and non-motor symptoms, significantly affecting patients' …

Parkinson's disease is a progressive neurodegenerative disorder. The classical motor
symptoms include resting tremors, bradykinesia, rigidity and postural instability and are …

Reactive oxygen and nitrogen species change cellular responses through diverse
mechanisms that are now being defined. At low levels, they are signalling molecules, and at …

Parkinson disease (PD) is a multifactorial neurodegenerative disorder, the etiology of which
remains largely unknown. Progressive impairment of voluntary motor control, which …

Alzheimer disease (AD) and Parkinson disease (PD) are the two most common age-related
neurodegenerative diseases characterized by prominent neurodegeneration in selective …