Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future

J Zhou, G Yu, F Huang - Chemical Society Reviews, 2017 - pubs.rsc.org
Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …

Supramolecular amphiphiles based on host–guest molecular recognition motifs

G Yu, K Jie, F Huang - Chemical reviews, 2015 - ACS Publications
Self-assembly, which makes use of molecules rather than atomic units, offers a bottom-up
approach to the construction of new materials on multiple length scales.(1-9) By precisely …

Hollow mesoporous silica nanoparticles facilitated drug delivery via cascade pH stimuli in tumor microenvironment for tumor therapy

J Liu, Z Luo, J Zhang, T Luo, J Zhou, X Zhao, K Cai - Biomaterials, 2016 - Elsevier
To efficiently deliver anti-cancer drug to tumor site and reduce its toxic side effects on normal
tissues, a polyethylene glycol (PEG) shielding and tumor microenvironment triggering …

Cucurbituril-based supramolecular engineered nanostructured materials

S Gürbüz, M Idris, D Tuncel - Organic & biomolecular chemistry, 2015 - pubs.rsc.org
Cucurbituril (CB) is a unique macrocycle with a rigid symmetrical structure, which is
composed of two identical hydrophilic portals decorated with partially negatively charged …

Emerging supramolecular therapeutic carriers based on host–guest interactions

AA Karim, Q Dou, Z Li, XJ Loh - Chemistry–An Asian Journal, 2016 - Wiley Online Library
Recent advances in host–guest chemistry have significantly influenced the construction of
supramolecular soft biomaterials. The highly selective and non‐covalent interactions …

Cucurbit [8] uril-based giant supramolecular vesicles: highly stable, versatile carriers for photoresponsive and targeted drug delivery

C Hu, N Ma, F Li, Y Fang, Y Liu, L Zhao… - … applied materials & …, 2018 - ACS Publications
Highly stable giant supramolecular vesicles were constructed by hierarchical self-assembly
of cucurbit [8] uril (CB [8])-based supra-amphiphiles for photoresponsive and targeted …

Orthogonal design of supramolecular prodrug vesicles via water-soluble pillar [5] arene and betulinic acid derivative for dual chemotherapy

G Sun, M Zuo, Z Xu, K Wang, L Wang… - ACS Applied Bio …, 2022 - ACS Publications
Supramolecular prodrug vesicles with efficient property for dual chemotherapy have been
successfully constructed based on the orthogonal self-assembly between a water-soluble …

Soft supramolecular nanoparticles by noncovalent and host–guest interactions

C Stoffelen, J Huskens - Small, 2016 - Wiley Online Library
Supramolecular chemistry provides a tool for the formation of highly ordered structures by
means of noncovalent interactions. Soft supramolecular nanoparticles are self‐assembled …

Supramolecular nanoparticles constructed by DOX-based prodrug with water-soluble pillar [6] arene for self-catalyzed rapid drug release

Y Cao, Y Li, XY Hu, X Zou, S **ong, C Lin… - Chemistry of …, 2015 - ACS Publications
The constructing of novel supramolecular prodrug nanoparticles based on the host–guest
interaction of water-soluble pillar [6] arene (WP6) and novel doxorubicin (DOX)-based …

Cucurbit [8] uril‐Based Polymers and Polymer Materials

H Zou, J Liu, Y Li, X Li, X Wang - Small, 2018 - Wiley Online Library
Abstract Cucurbit [8] uril (CB [8]) is unique and notable in the cucurbit [n] uril family, since it
has a relatively large cavity and thus is able to simultaneously accommodate two guest …