Parkinson's disease (PD) affects 1–2 per 1000 of the population at any time. PD prevalence
is increasing with age and PD affects 1% of the population above 60 years. The main …

The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

Although most cases of Alzheimer's and Parkinson's disease are sporadic, some cases are
clearly familial. This review, part of the Genomic Medicine series, examines the genetics of …

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder that
results primarily from the death of dopaminergic neurons in the substantia nigra. Although …

Recent investigation into the mechanisms of Parkinson's disease (PD) has generated
remarkable insight while simultaneously challenging traditional conceptual frameworks …

Parkinson disease is a complex, multifactorial neurodegenerative disease. Although a
heritable basis was originally thought unlikely, recent studies have implicated several genes …

Although the causes of Parkinson's disease (PD) are thought to be primarily environmental,
recent studies suggest that a number of genes influence susceptibility. Using targeted case …

Parkinson's disease arises from genetic and possibly neurotoxic causes that produce
massive cell death of the neuromelanin-containing dopaminergic neurons of the substantia …

Research into the pathogenesis of Parkinson's disease has been rapidly advanced by the
development of animal models. Initial models were developed by using toxins that …

Coffee can be an ally in the fight against diseases such as type 2 diabetes, cancer, hepatic
injury, cirrhosis, depression, suicidal behavior, and neurological and cardiovascular …