Protein–RNA interactions are of vital importance to a variety of cellular activities. Both
experimental and computational techniques have been developed to study the interactions …

Proteins interact with a variety of molecules including proteins and nucleic acids. We review
a comprehensive collection of over 50 studies that analyze and/or predict these interactions …

Motivation Accurate predictions of protein-binding residues (PBRs) enhances understanding
of molecular-level rules governing protein–protein interactions, helps protein–protein …

Current predictors of DNA-binding residues (DBRs) from protein sequences belong to two
distinct groups, those trained on binding annotations extracted from structured protein-DNA …

Motivation Proteins usually perform their functions by interacting with other proteins, which is
why accurately predicting protein–protein interaction (PPI) binding sites is a fundamental …

Parkinson's disease (PD) is a prevalent neurodegenerative disease for which robust
biomarkers are needed. Because protein structure reflects function, we tested whether …

Motivation Proteases are enzymes that cleave target substrate proteins by catalyzing the
hydrolysis of peptide bonds between specific amino acids. While the functional proteolysis …

Motivation Intrinsically disordered protein regions interact with proteins, nucleic acids and
lipids. Regions that bind lipids are implicated in a wide spectrum of cellular functions and …

Predicting protein structure from sequence alone is challenging. Thus, the majority of
methods for protein structure prediction rely on evolutionary information from multiple …

We present DescribePROT, the database of predicted amino acid-level descriptors of
structure and function of proteins. DescribePROT delivers a comprehensive collection of 13 …