High parameter imaging is an important tool in the life sciences for both discovery and
healthcare applications. Imaging Mass Cytometry (IMC) and Multiplexed Ion Beam Imaging …

Fluorescence image co-localization analysis is widely utilized to suggest biomolecular
interaction. However, there exists some confusion as to its correct implementation and …

Lipid droplets (LDs) are intracellular lipid-rich organelles that regulate the storage of neutral
lipids and were recently found to be involved in many physiological processes, metabolic …

Anticancer therapy screening in vitro identifies additional treatments and improves clinical
outcomes. Systematically, although most tested cells respond to cues with apoptosis, an …

We present a new plugin for ImageJ called DiAna, for Distance Analysis, which comes with a
user-friendly interface. DiAna proposes robust and accurate 3D segmentation for object …

The intracellular bacteria Legionella pneumophila encodes a type IV secretion system
(T4SS) that injects effector proteins into macrophages in order to establish and replicate …

Physical forces are essential to biological function, but their impact at the tissue level is not
fully understood. The gut is under continuous mechanical stress because of peristalsis. To …

Super-resolution optical imaging based on the switching and localization of individual
fluorescent molecules [photoactivated localization microscopy (PALM), stochastic optical …

Modern biological research particularly in the fields of developmental and cell biology has
been transformed by the rapid evolution of the light microscope. The light microscope, long a …

At the center of cell biology is our ability to image the cell and its various components, either
in isolation or within an organism. Given its importance, biological imaging has emerged as …