In situ self-assembly for cancer therapy and imaging

J Kim, S Lee, Y Kim, M Choi, I Lee, E Kim… - Nature Reviews …, 2023 - nature.com
In situ self-assembly—the in situ formation of complex materials via biochemical reactions of
monomers—has enhanced the efficacy of drug delivery for cancer therapy and imaging. So …

Biomaterials tools to modulate the tumour microenvironment in immunotherapy

Y Chao, Z Liu - Nature Reviews Bioengineering, 2023 - nature.com
Cancer immunotherapies, such as immune checkpoint blockade and chimeric antigen
receptor (CAR) T cell therapy, have transformed clinical oncology. However, limited patient …

Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Fluorescence image-guided tumour surgery

K Wang, Y Du, Z Zhang, K He, Z Cheng, L Yin… - Nature Reviews …, 2023 - nature.com
Intraoperative fluorescent imaging can provide real-time identification of tumours, lymph
nodes, nerves and other healthy and malignant tissues during oncological surgery …

Luminescent and photofunctional transition metal complexes: From molecular design to diagnostic and therapeutic applications

LCC Lee, KKW Lo - Journal of the American Chemical Society, 2022 - ACS Publications
There has been emerging interest in the exploitation of the photophysical and
photochemical properties of transition metal complexes for diagnostic and therapeutic …

High performance of simple organic phosphorescence host–guest materials and their application in time‐resolved bioimaging

Y Wang, H Gao, J Yang, M Fang, D Ding… - Advanced …, 2021 - Wiley Online Library
The study of purely organic room‐temperature phosphorescence (RTP) has drawn
increasing attention because of its considerable theoretical research and practical …

In situ hypoxia-induced supramolecular perylene diimide radical anions in tumors for photothermal therapy with improved specificity

H Wang, KF Xue, Y Yang, H Hu, JF Xu… - Journal of the American …, 2022 - ACS Publications
Considering that hypoxia is closely associated with tumor proliferation, invasion, metastasis,
and drug resistance, it is of great significance to overcome hypoxia in tumor treatment …

Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics

P Mi - Theranostics, 2020 - pmc.ncbi.nlm.nih.gov
In recent years, much progress has been motivated in stimuli-responsive nanocarriers,
which could response to the intrinsic physicochemical and pathological factors in diseased …

Early detection of pancreatic cancer

SP Pereira, L Oldfield, A Ney, PA Hart… - The lancet …, 2020 - thelancet.com
Pancreatic ductal adenocarcinoma is most frequently detected at an advanced stage. Such
late detection restricts treatment options and contributes to a dismal 5-year survival rate of 3 …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …