Dangers of hyperoxia

M Singer, PJ Young, JG Laffey, P Asfar, FS Taccone… - Critical Care, 2021 - Springer
Oxygen (O 2) toxicity remains a concern, particularly to the lung. This is mainly related to
excessive production of reactive oxygen species (ROS). Supplemental O 2, ie inspiratory O …

Perioperative lung protective ventilation

B O'Gara, D Talmor - Bmj, 2018 - bmj.com
Perioperative lung injury is a major source of postoperative morbidity, excess healthcare
use, and avoidable mortality. Many potential inciting factors can lead to this condition …

Effect of intraoperative high positive end-expiratory pressure (PEEP) with recruitment maneuvers vs low PEEP on postoperative pulmonary complications in obese …

T Bluth, AS Neto, MJ Schultz, P Pelosi, MG de Abreu - Jama, 2019 - jamanetwork.com
Importance An intraoperative higher level of positive end-expiratory positive pressure
(PEEP) with alveolar recruitment maneuvers improves respiratory function in obese patients …

Effect of intraoperative low tidal volume vs conventional tidal volume on postoperative pulmonary complications in patients undergoing major surgery: a randomized …

D Karalapillai, L Weinberg, P Peyton, L Ellard, R Hu… - Jama, 2020 - jamanetwork.com
Importance In patients who undergo mechanical ventilation during surgery, the ideal tidal
volume is unclear. Objective To determine whether low-tidal-volume ventilation compared …

Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery: pragmatic, double blinded, multicentre randomised …

I Boden, EH Skinner, L Browning, J Reeve, L Anderson… - bmj, 2018 - bmj.com
Objective To assess the efficacy of a single preoperative physiotherapy session to reduce
postoperative pulmonary complications (PPCs) after upper abdominal surgery. Design …

The LAS VEGAS risk score for prediction of postoperative pulmonary complications: an observational study

AS Neto, LGV da Costa, SNT Hemmes… - European Journal of …, 2018 - journals.lww.com
BACKGROUND Currently used pre-operative prediction scores for postoperative pulmonary
complications (PPCs) use patient data and expected surgery characteristics exclusively …

Perioperative management of obese patient

S Bazurro, L Ball, P Pelosi - Current opinion in critical care, 2018 - journals.lww.com
Obese patients are at higher risk of perioperative complications, mainly associated with
those related to the respiratory function. An appropriate preoperative evaluation …

Individualized versus fixed positive end-expiratory pressure for intraoperative mechanical ventilation in obese patients: a secondary analysis

P Simon, F Girrbach, D Petroff, N Schliewe… - …, 2021 - ingentaconnect.com
Background: General anesthesia may cause atelectasis and deterioration in oxygenation in
obese patients. The authors hypothesized that individualized positive end-expiratory …

Epidemiology and clinical course of primary biliary cholangitis in the Asia–Pacific region: a systematic review and meta-analysis

NA Zeng, W Duan, S Chen, S Wu, H Ma, X Ou… - Hepatology …, 2019 - Springer
Aims Epidemiological studies on primary biliary cholangitis (PBC) show heterogeneity. The
aim of the present study was to synthesize the prevalence, incidence and clinical course of …

[HTML][HTML] Intraoperative ventilation strategies to prevent postoperative pulmonary complications: a network meta-analysis of randomised controlled trials

QW Deng, WC Tan, BC Zhao, SH Wen, JT Shen… - British Journal of …, 2020 - Elsevier
Background The debate on lung-protective ventilation strategies for surgical patients is
ongoing. Evidence suggests that the use of low tidal volume VT improves clinical outcomes …