Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Clinical perspective of antimicrobial resistance in bacteria

Y Zhu, WE Huang, Q Yang - Infection and drug resistance, 2022 - Taylor & Francis
Antimicrobial resistance (AMR) has become a global clinical problem in recent years. With
the discovery of antibiotics, infections were not a deadly problem for clinicians as they used …

Assessment of the UV/Chlorine Process in the Disinfection of Pseudomonas aeruginosa: Efficiency and Mechanism

L Wang, C Ye, L Guo, C Chen, X Kong… - Environmental …, 2021 - ACS Publications
UV irradiation and chlorination have been widely used for water disinfection. However, there
are some limitations, such as the risk of generating viable but nonculturable bacteria and …

Raman spectroscopy and machine learning for the classification of breast cancers

L Zhang, C Li, D Peng, X Yi, S He, F Liu… - … Acta Part A: Molecular …, 2022 - Elsevier
Breast cancer is a major health threat for women. The drug responses associated with
different breast cancer subtypes have obvious effects on therapeutic outcomes; therefore …

Phenazine production promotes antibiotic tolerance and metabolic heterogeneity in Pseudomonas aeruginosa biofilms

KT Schiessl, F Hu, J Jo, SZ Nazia, B Wang… - Nature …, 2019 - nature.com
Antibiotic efficacy can be antagonized by bioactive metabolites and other drugs present at
infection sites. Pseudomonas aeruginosa, a common cause of biofilm-based infections …

Optical imaging of metabolic dynamics in animals

L Shi, C Zheng, Y Shen, Z Chen, ES Silveira… - Nature …, 2018 - nature.com
Direct visualization of metabolic dynamics in living animals with high spatial and temporal
resolution is essential to understanding many biological processes. Here we introduce a …

Recent developments in Raman spectral analysis of microbial single cells: Techniques and applications

H Jayan, H Pu, DW Sun - Critical Reviews in Food Science and …, 2022 - Taylor & Francis
The conventional microbial cell analyses are mostly population-averaged methods that
conceal the characteristics of single-cell in the community. Single-cell analysis can provide …

Active antibiotic resistome in soils unraveled by single-cell isotope probing and targeted metagenomics

HZ Li, K Yang, H Liao, SB Lassen… - Proceedings of the …, 2022 - National Acad Sciences
Antimicrobial resistance (AMR) in soils represents a serious risk to human health through
the food chain and human–nature contact. However, the active antibiotic-resistant bacteria …

Positive dielectrophoresis–based Raman-activated droplet sorting for culture-free and label-free screening of enzyme function in vivo

X Wang, Y **n, L Ren, Z Sun, P Zhu, Y Ji, C Li, J Xu… - Science …, 2020 - science.org
The potential of Raman-activated cell sorting (RACS) is inherently limited by conflicting
demands for signal quality and sorting throughput. Here, we present positive …

Development of SERS tags for human diseases screening and detection

T Gong, CM Das, MJ Yin, TR Lv, NM Singh… - Coordination Chemistry …, 2022 - Elsevier
Recent advances in surface-enhanced Raman scattering (SERS) have offered great
promise for the early-stage diagnosis of life-threatening diseases by in vivo sensing and …