Toward Mechanistic Understanding of Mechanochemical Reactions Using Real-Time In Situ Monitoring

S Lukin, LS Germann, T Friščić… - Accounts of chemical …, 2022 - ACS Publications
Conspectus The past two decades have witnessed a rapid emergence of interest in
mechanochemistry–chemical and materials reactivity achieved or sustained by the action of …

Mechanochemistry in organic synthesis: An Italian journey through innovations

F Basoccu, L De Luca… - European Journal of …, 2024 - Wiley Online Library
Mechanochemistry, as an enabling technology, harnesses mechanical force to drive
chemical reactions, presenting compelling advantages in organic synthesis within the …

Methods for monitoring milling reactions and mechanistic studies of mechanochemistry: a primer

PA Julien, T Friščić - Crystal Growth & Design, 2022 - ACS Publications
Mechanochemistry by ball milling is garnering significant attention as an efficient and
versatile means of chemical synthesis which minimizes the need for solvents and reduces …

Topological and physical links in soft matter systems

E Orlandini, C Micheletti - Journal of Physics: Condensed Matter, 2021 - iopscience.iop.org
Linking, or multicomponent topological entanglement, is ubiquitous in soft matter systems,
from mixtures of polymers and DNA filaments packed in vivo to interlocked line defects in …

[HTML][HTML] In situ synchrotron X-ray diffraction studies monitoring mechanochemical reactions of hard materials: Challenges and limitations

T Rathmann, H Petersen, S Reichle… - Review of Scientific …, 2021 - pubs.aip.org
In situ monitoring of mechanochemical reactions of soft matter is feasible by synchrotron
diffraction experiments. However, so far, reactions of hard materials in existing polymer …

Fast, solvent-free synthesis of ferrocene-containing organic cages via dynamic covalent chemistry in the solid state

T Kunde, T Pausch, PA Guńka, M Krzyżanowski… - Chemical …, 2022 - pubs.rsc.org
A simple, solvent-free synthetic protocol towards the synthesis of organic self-assembled
macromolecules has been established. By employing mechanochemistry using glassware …

Operando acoustic analysis: a valuable method for investigating reaction mechanisms in mechanochemistry

C Leroy, S Mittelette, G Félix, N Fabregue… - Chemical …, 2022 - pubs.rsc.org
We present a new operando approach for following reactions taking place in
mechanochemistry, relying on the analysis of the evolution of the sound during milling. We …

Computational evaluation of halogen-bonded cocrystals enables prediction of their mechanochemical interconversion reactions

L Kumar, K Leko, V Nemec, D Trzybiński… - Chemical …, 2023 - pubs.rsc.org
Periodic density-functional theory (DFT) calculations were used to predict the
thermodynamic stability and the likelihood of interconversion between a series of halogen …

The mechanochemical beckmann rearrangement over solid acids: From the ball mill to the extruder

DM Baier, T Rensch, D Dobreva, C Spula… - Chemistry …, 2023 - Wiley Online Library
Beckmann rearrangement was carried out in the solid state in a ball mill using metal oxides
as solid acids. After a comprehensive investigation of different reaction parameters, acids as …

Listening to the Formation of Polymorphs in a Ball Mill

ÉMS Parlier, K Al Amir, TX Métro, P Granjon… - Analytical …, 2025 - ACS Publications
In this contribution, we apply our newly developed ball-milling operando platform, which
combines Raman spectroscopy and thermal (IR) imaging, as well as acoustic and high …