Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular …

L István, C Czakó, Á Élő, Z Mihály, P Sótonyi, A Varga… - Geroscience, 2021 - Springer
Carotid artery stenosis (CAS) is a consequence of systemic atherosclerotic disease affecting
the aging populations of the Western world. CAS is frequently associated with cognitive …

Self-supervised learning for accurately modelling hierarchical evolutionary patterns of cerebrovasculature

B Guo, Y Chen, J Lin, B Huang, X Bai, C Guo… - Nature …, 2024 - nature.com
Cerebrovascular abnormalities are critical indicators of stroke and neurodegenerative
diseases like Alzheimer's disease (AD). Understanding the normal evolution of brain vessels …

Are the variants of the circle of Willis determined by genetic or environmental factors? Results of a twin study and review of the literature

B Forgo, AD Tarnoki, DL Tarnoki, DT Kovacs… - Twin Research and …, 2018 - cambridge.org
Background: Anatomic variants of the circle of Willis (CW) are commonly observed in healthy
subjects. Genetic and environmental factors influencing these variants remain unclear. Our …

Assessment of cerebral autoregulatory function and inter-hemispheric blood flow in older adults with internal carotid artery stenosis using transcranial Doppler …

R Magyar-Stang, H Pál, B Csányi, A Gaál, Z Mihály… - Geroscience, 2023 - Springer
Unhealthy vascular aging promotes atherogenesis, which may lead to significant internal
carotid artery stenosis (CAS) in 5 to 7.5% of older adults. The pathogenic factors that …

Understanding perioperative risk determinants in carotid endarterectomy: the impact of compromised circle of Willis morphology on inter-hemispheric blood flow …

Z Czinege, ÁD Sándor, D Gyürki, A Varga, T Csípő… - Geroscience, 2024 - Springer
Carotid artery stenosis (CAS) often requires surgical intervention through carotid
endarterectomy (CEA) to prevent stroke. Accurate cerebrovascular risk assessments are …

Demographic age-related variation in circle of Willis completeness assessed by digital subtraction angiography

RG Eaton, VS Shah, D Dornbos III… - Brain …, 2020 - journals.lww.com
OBJECTIVE: Incomplete circle of Willis (CoW) configuration is an important risk factor for
cerebrovascular pathology, namely aneurysm formation and ischemic stroke. This study was …

Initial and follow-up high-resolution vessel wall MRI study of spontaneous cervicocranial artery dissection

X Lin, W Guo, D She, Y Kang, Z **ng, D Cao - European Radiology, 2024 - Springer
Objectives To explore the factors associated with ischemic stroke secondary to spontaneous
cervicocranial artery dissection (sCCAD) and evaluate the initial imaging markers related to …

[HTML][HTML] The effect of circle of Willis morphology on retinal blood flow in patients with carotid stenosis measured by optical coherence tomography angiography

Z Mihály, L István, C Czakó, F Benyó… - Journal of Clinical …, 2023 - mdpi.com
The Circle of Willis (CoW) is the main collateral system, and its morphological variants are
more common in patients who have severe carotid artery stenosis. Earlier data suggest that …

[HTML][HTML] Machine learning-based pulse wave analysis for classification of circle of Willis topology: An in silico study with 30,618 virtual subjects

A Sen, M Aguirre, PH Charlton, L Navarro… - … Signal Processing and …, 2025 - Elsevier
Abstract Background and Objective The topology of the circle of Willis (CoW) is crucial in
cerebral circulation and significantly impacts patient management. Incomplete CoW …

Morphologic variants of the Cerebral Arterial Circle on computed tomographic angiography (CTA): a large retrospective study

B Coulier - Surgical and Radiologic Anatomy, 2021 - Springer
Purpose To confirm and illustrate the great variability of morphology of the Cerebral Arterial
Circle (CAC)—also commonly called “Circle of Willis”—in current clinical Computed …