Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …

The actin cortex is a thin layer of actin, myosin and actin-binding proteins that underlies the
membrane of most animal cells. It is highly dynamic and can undergo remodelling on …

Myosin-driven contraction of the actin cytoskeleton is at the base of cell and tissue
morphogenesis. At the molecular level, myosin motors drive contraction by sliding actin …

In animal cells, shape is mostly determined by the actomyosin cortex, a thin cytoskeletal
network underlying the plasma membrane. Myosin motors generate tension in the cortex …

The actomyosin cytoskeleton is responsible for most force-driven processes in cells and
tissues. How it assembles into the necessary structures at the right time and place is an …

Most metazoan cells entering mitosis undergo characteristic rounding, which is important for
accurate spindle positioning and chromosome separation. Rounding is driven by contractile …

Mitotic cell divisions increase cell number while faithfully distributing the replicated genome
at each division. The Caenorhabditis elegans embryo is a powerful model for eukaryotic cell …

Cytoskeletal networks of actin filaments and myosin motors drive many dynamic cell
processes. A key characteristic of these networks is their contractility. Despite intense …

The adaptive in vivo mechanisms underlying the switch in Salmonella enterica lifestyles
from the infectious form to a dormant form remain unknown. We employed Caenorhabditis …

The mechanical properties of the actin cortex regulate shape changes during cell division,
cell migration, and tissue morphogenesis. We show that modulation of myosin II (MII) …