Protein kinases play a major role in cellular activation processes, including signal
transduction by diverse immunoreceptors. Given their roles in cell growth and death and in …

In the last few decades, there has been a growing interest in Bruton's tyrosine kinase (BTK)
and the compounds that target it. BTK is a downstream mediator of the B-cell receptor (BCR) …

COVID-19 has impacted billions of people since 2019 and unfolded a major healthcare
crisis. With an increasing number of deaths and the emergence of more transmissible …

Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Patients with lymphoproliferative diseases (LPD) are vulnerable to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection. Here, we describe and analyze the …

The emergence of the new SARS-CoV-2 virus, which causes the disease known as COVID-
19, has generated a pandemic that has plunged the world into a health crisis. The infection …

Background Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to
COVID-19 related poor outcomes, including thrombosis and death, due to the advanced …

Since the beginning of the COVID-19 pandemic, the scientific community has focused on
prophylactic vaccine development. In parallel, the experience of the pharmacotherapy of this …

Tetrabromobisphenol A (TBBPA) is a potent flame retardant used in numerous appliances
and a major pollutant in households and ecosystems. In vertebrates, it was shown to affect …

The respiratory illness known as COVID-19 is caused by the novel coronavirus, SARS-CoV-
2. While the precise pathogenic mechanism of COVID-19 remains unclear, the occurrence of …