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[HTML][HTML] Symbionts and gene drive: two strategies to combat vector-borne disease
Mosquitoes bring global health problems by transmitting parasites and viruses such as
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …
Gene drive and symbiont technologies for control of mosquito-borne diseases
Mosquito-borne diseases, such as dengue and malaria, pose a significant burden to global
health. Current control strategies with insecticides are only moderately effective. Scalable …
health. Current control strategies with insecticides are only moderately effective. Scalable …
Germline Cas9 promoters with improved performance for homing gene drive
J Du, W Chen, X Jia, X Xu, E Yang, R Zhou… - Nature …, 2024 - nature.com
Gene drive systems could be a viable strategy to prevent pathogen transmission or suppress
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …
vector populations by propagating drive alleles with super-Mendelian inheritance. CRISPR …
[CARTE][B] Insect physiology and biochemistry
JL Nation Sr - 2022 - taylorfrancis.com
Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …
Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails
Population-scale genome modification can alter the composition or fate of wild populations.
Synthetic gene drives provide one set of tools, but their use is complicated by scientific …
Synthetic gene drives provide one set of tools, but their use is complicated by scientific …
[HTML][HTML] CRISPR-based genetic control strategies for insect pests
YAN Ying, RA Aumann, I Häcker… - Journal of Integrative …, 2023 - Elsevier
Genetic control strategies such as the sterile insect technique have successfully fought
insect pests worldwide. The CRISPR (clustered regularly interspaced short palindromic …
insect pests worldwide. The CRISPR (clustered regularly interspaced short palindromic …
Knockout of the odorant receptor co-receptor, orco, impairs feeding, mating and egg-laying behavior in the fall armyworm Spodoptera frugiperda
H Sun, LA Bu, SC Su, D Guo, CF Gao, SF Wu - Insect Biochemistry and …, 2023 - Elsevier
The olfactory transduction system of insects is involved in multiple behavioral processes
such as foraging, mating, and egg-laying behavior. In the insect olfactory receptor neurons …
such as foraging, mating, and egg-laying behavior. In the insect olfactory receptor neurons …
Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila
W Chen, J Guo, Y Liu, J Champer - Nature Communications, 2024 - nature.com
CRISPR homing gene drives can suppress pest populations by targeting female fertility
genes, converting wild-type alleles into drive alleles in the germline of drive heterozygotes …
genes, converting wild-type alleles into drive alleles in the germline of drive heterozygotes …
[PDF][PDF] A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles
Gene drives are engineered alleles that can bias inheritance in their favor, allowing them to
spread throughout a population. They could potentially be used to modify or suppress pest …
spread throughout a population. They could potentially be used to modify or suppress pest …
Suppression gene drive in continuous space can result in unstable persistence of both drive and wild‐type alleles
Rapid evolutionary processes can produce drastically different outcomes when studied in
panmictic population models vs. spatial models. One such process is gene drive, which …
panmictic population models vs. spatial models. One such process is gene drive, which …