A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - journals.asm.org
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The microbiota-gut-brain axis: from motility to mood

KG Margolis, JF Cryan, EA Mayer - Gastroenterology, 2021 - Elsevier
The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Understanding the gut–brain axis and its therapeutic implications for neurodegenerative disorders

Y Zheng, L Bonfili, T Wei, AM Eleuteri - Nutrients, 2023 - mdpi.com
The gut–brain axis (GBA) is a complex bidirectional communication network connecting the
gut and brain. It involves neural, immune, and endocrine communication pathways between …

The impact of the microbiota-gut-brain axis on Alzheimer's disease pathophysiology

T Doifode, VV Giridharan, JS Generoso, G Bhatti… - Pharmacological …, 2021 - Elsevier
The gut microbiota is a complex ecosystem that comprises of more than 100 trillion symbiotic
microbial cells. The microbiota, the gut, and the brain form an association,'the microbiota-gut …

Intestinal barrier and gut microbiota: Sha** our immune responses throughout life

T Takiishi, CIM Fenero, NOS Câmara - Tissue barriers, 2017 - Taylor & Francis
The gastrointestinal (GI) tract is considered the largest immunological organ in the body
having a central role in regulating immune homeostasis. Contrary to earlier belief, the …

Boundaries and integration between microbiota, the nervous system, and immunity

AJ Macpherson, V Pachnis, M Prinz - Immunity, 2023 - cell.com
The enteric nervous system is largely autonomous, and the central nervous system is
compartmentalized behind the blood-brain barrier. Yet the intestinal microbiota shapes gut …

Neuronal programming by microbiota regulates intestinal physiology

Y Obata, Á Castaño, S Boeing, AC Bon-Frauches… - Nature, 2020 - nature.com
Neural control of the function of visceral organs is essential for homeostasis and health.
Intestinal peristalsis is critical for digestive physiology and host defence, and is often …

Prebiotics and probiotics in digestive health

EMM Quigley - Clinical Gastroenterology and Hepatology, 2019 - Elsevier
As the importance of the gut microbiota in health and disease is increasingly recognized
interest in interventions that can modulate the microbiota and its interactions with its host has …

Gut microbiome and aging: Physiological and mechanistic insights

R Nagpal, R Mainali, S Ahmadi… - … and healthy aging, 2018 - journals.sagepub.com
The development of human gut microbiota begins as soon as the neonate leaves the
protective environment of the uterus (or maybe in-utero) and is exposed to innumerable …