Motivation fastsimcoal2 extends fastsimcoal, a continuous time coalescent-based genetic
simulation program, by enabling the estimation of demographic parameters under very …

Increasing habitat fragmentation leads to wild populations becoming small, isolated, and
threatened by inbreeding depression. However, small populations may be able to purge …

Genomic studies of endangered species have primarily focused on describing diversity
patterns and resolving phylogenetic relationships, with the overarching goal of informing …

The tiger (Panthera tigris) is a charismatic megafauna species that originated and diversified
in Asia and probably experienced population contraction and expansion during the …

Poaching and trafficking have a substantial negative impact on the population growth and
range expansion of the Chinese pangolin (Manis pentadactyla). However, recently reported …

Unprecedented advances in sequencing technology in the past decade allow a better
understanding of genetic variation and its partitioning in natural populations. Such inference …

Despite increasing threats of extinction to Elasmobranchii (sharks and rays), whole genome-
based conservation insights are lacking. Here, we present chromosome-level genome …

Abstract The South China tiger (Panthera tigris amoyensis, SCT) is the most critically
endangered subspecies of tiger due to functional extinction in the wild. Inbreeding …

Abstract Background The lion (Panthera leo) is one of the most popular and iconic feline
species on the planet, yet in spite of its popularity, the last century has seen massive …

Most endangered species exist today in small populations, many of which are isolated.
Evolution in such populations is largely governed by genetic drift. Empirical evidence for drift …