Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases

S Bulotta, M Celano, SM Lepore, T Montalcini… - Journal of translational …, 2014 - Springer
The overall health beneficial action of olive oil phenolic components is well established.
Recent studies have elucidated the biological effects of two isolated compounds, namely …

[HTML][HTML] Biological activities of the natural antioxidant oleuropein: Exceeding the expectation–A mini-review

I Hassen, H Casabianca, K Hosni - Journal of Functional Foods, 2015 - Elsevier
An emerging body of evidence indicates that oleuropein, a biophenol usually found in olive
leaves, extra-virgin olive oil and in some species of the Oleaceae family has potent …

Amelioration of Ethanol-Induced Gastric Ulcers in Rats Pretreated with Phycobiliproteins of Arthrospira (Spirulina) Maxima

O Guzmán-Gómez, RV García-Rodríguez… - Nutrients, 2018 - mdpi.com
Phycobiliproteins of Arthrospira (Spirulina) maxima have attracted attention because of their
potential therapeutic antioxidant properties. The aim of this study was to assess the possible …

[HTML][HTML] Membrane composition and dynamics: a target of bioactive virgin olive oil constituents

S Lopez, B Bermudez, S Montserrat-De La Paz… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The endogenous synthesis of lipids, which requires suitable dietary raw materials, is critical
for the formation of membrane bilayers. In eukaryotic cells, phospholipids are the …

[HTML][HTML] A review of the most common in vivo models of stomach ulcers and natural and synthetic anti-ulcer compounds: a comparative systematic study

M Beiranvand - Phytomedicine Plus, 2022 - Elsevier
Background Peptic ulcer disease (stomach and duodenal ulcers) is one of the most painful
diseases, affecting an estimated 4 million Americans, according to a new statistic, and will …

The double-edged sword of oleuropein in ovarian cancer cells: From antioxidant functions to cytotoxic effects

S Scicchitano, E Vecchio, AM Battaglia… - International Journal of …, 2023 - mdpi.com
Oleuropein plays a key role as a pro-oxidant as well as an antioxidant in cancer. In this
study, the activity of oleuropein, in an in vitro model of ovarian (OCCs) and breast cancer …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …

Protective effects of friedelin isolated from Azima tetracantha Lam. against ethanol-induced gastric ulcer in rats and possible underlying mechanisms

P Antonisamy, V Duraipandiyan, A Aravinthan… - European Journal of …, 2015 - Elsevier
The current study was aimed to investigate the gastroprotective effects of friedelin isolated
from the hexane extract of leaves of Azima tetracantha. Ethanol-induced gastric ulcer model …

An up-date of olive oil phenols in inflammation and cancer: molecular mechanisms and clinical implications

A Cárdeno, M Sánchez-Hidalgo… - Current Medicinal …, 2013 - benthamdirect.com
Olive oil (OO), the main fatty component of the Mediterranean diet, exhibits numerous
biological functions which are beneficial for the state of health. In addition to …

The olive-tree leaves as a source of high-added value molecules: Oleuropein

LAS Cavaca, IM López-Coca, G Silvero… - Studies in natural …, 2020 - Elsevier
Plants are one of the most important sources of natural bioactive products. Olive oil and olive
fruits contain a large variety of beneficial phenolic compounds. Epidemiological studies …