Bionanoparticles in cancer imaging, diagnosis, and treatment
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …
[HTML][HTML] Applications and developments of gene therapy drug delivery systems for genetic diseases
X Pan, H Veroniaina, N Su, K Sha, F Jiang… - Asian journal of …, 2021 - Elsevier
Genetic diseases seriously threaten human health and have always been one of the
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …
refractory conditions facing humanity. Currently, gene therapy drugs such as siRNA, shRNA …
MicroRNA-129 and-335 promote diabetic wound healing by inhibiting Sp1-mediated MMP-9 expression
W Wang, C Yang, XY Wang, LY Zhou, GJ Lao, D Liu… - Diabetes, 2018 - Am Diabetes Assoc
Diabetic wounds are recalcitrant to healing. However, the mechanism causing this
dysfunction is not fully understood. High expression of matrix metalloproteinase-9 (MMP-9) …
dysfunction is not fully understood. High expression of matrix metalloproteinase-9 (MMP-9) …
TRAIL-based gene delivery and therapeutic strategies
H Zhong, H Wang, J Li, Y Huang - Acta Pharmacologica Sinica, 2019 - nature.com
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand), also known as APO2L,
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …
belongs to the tumor necrosis factor family. By binding to the death receptor 4 (DR4) or DR5 …
Towards clinical implementation of adeno-associated virus (AAV) vectors for cancer gene therapy: current status and future perspectives
UT Hacker, M Bentler, D Kaniowska, M Morgan… - Cancers, 2020 - mdpi.com
Adeno-associated virus (AAV) vectors have gained tremendous attention as in vivo delivery
systems in gene therapy for inherited monogenetic diseases. First market approvals …
systems in gene therapy for inherited monogenetic diseases. First market approvals …
Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis
Sonodynamic therapy (SDT) is a noninvasive therapeutic method via the activation of certain
chemical sensitizers using low intensity ultrasound. In this work, we evaluated the antitumor …
chemical sensitizers using low intensity ultrasound. In this work, we evaluated the antitumor …
MicroRNA-based drugs for brain tumors
S Anthiya, A Griveau, C Loussouarn, P Baril, M Garnett… - Trends in cancer, 2018 - cell.com
MicroRNAs (miRNAs) are key regulatory elements encoded by the genome. A single miRNA
can downregulate the expression of multiple genes involved in diverse functions. Because …
can downregulate the expression of multiple genes involved in diverse functions. Because …
MicroRNA-221: A fine tuner and potential biomarker of chronic liver injury
J Markovic, AD Sharma, A Balakrishnan - Cells, 2020 - mdpi.com
The last decade has witnessed significant advancements in our understanding of how small
noncoding RNAs, such as microRNAs (miRNAs), regulate disease progression. One such …
noncoding RNAs, such as microRNAs (miRNAs), regulate disease progression. One such …
Nitric oxide/paclitaxel micelles enhance anti-liver cancer effects and paclitaxel sensitivity by inducing ferroptosis, endoplasmic reticulum stress and pyroptosis
H Li, X Deng, Z Zhang, Z Yang, H Huang, X Ye… - RSC …, 2023 - pubs.rsc.org
The objective of this study was to investigate the anticancer activities of biodegradable
polymeric micelles composed of monomethoxy poly (ethylene glycol), polylactic acid, and …
polymeric micelles composed of monomethoxy poly (ethylene glycol), polylactic acid, and …
Recent advances in various adeno-associated viruses (AAVs) as gene therapy agents in hepatocellular carcinoma
M Hadi, O Qutaiba B. Allela, M Jabari, AM Jasoor… - Virology Journal, 2024 - Springer
Primary liver cancer, which is scientifically referred to as hepatocellular carcinoma (HCC), is
a significant concern in the field of global health. It has been demonstrated that conventional …
a significant concern in the field of global health. It has been demonstrated that conventional …