Glutamate is the major excitatory neurotransmitter in the central nervous system. Glutamate
transmission efficiency depends on the correct functionality and expression of a plethora of …

We all have a sense of time. Yet, there are no sensory receptors specifically dedicated for
perceiving time. It is an almost uniquely intangible sensation: we cannot see time in the way …

Neural circuits of the basal ganglia are critical for motor planning and action selection,,. Two
parallel basal ganglia pathways have been described, and have been proposed to exert …

Adult differentiated cells can be reprogrammed into pluripotent stem cells or lineage-
restricted proliferating precursors in culture; however, this has not been demonstrated in …

This review aims to classify and clarify, from a neuroanatomical, neurophysiological, and
psychological perspective, different memory models that are currently widespread in the …

Pleasure and motivation are important factors for goal-directed behavior and well-being in
both animals and humans. Intact hedonic capacity requires an undisturbed interplay …

Microglia are activated in many neurological diseases and have been suggested to play an
important role in the development of affective disorders including major depression. To …

Huntington's disease (HD) is caused by Huntingtin (Htt) gene mutation resulting in the loss
of striatal GABAergic neurons and motor functional deficits. We report here an in vivo cell …

Astrocytes are morphologically complex cells that serve essential roles. They are widely
implicated in central nervous system (CNS) disorders, with changes in astrocyte morphology …

The promise of using reprogrammed human neurons for disease modeling and regenerative
medicine relies on the ability to induce patient-derived neurons with high efficiency and …