Numerous studies have demonstrated that endothelial cells are capable of undergoing
endothelial to mesenchymal transition (EndMT), a newly recognized type of cellular …

Endothelial-to-mesenchymal transition is a dynamic process in which endothelial cells
suppress constituent endothelial properties and take on mesenchymal cell behaviors. To …

Aims/hypothesis The pathophysiology of diabetic retinopathy is linked to hyperglycaemia
and its effect on retinal microvascular tissues. The resulting endothelial injury changes the …

Cancer is one of the most important causes of morbidity and mortality worldwide. Tumor
cells grow in a complex microenvironment constituted of immune, stromal, and vascular cells …

microRNAs (miRNAs) are small, non-coding nucleotides that regulate diverse biological
processes. Altered microRNA biosynthesis or regulation contributes to pathological …

Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and
atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ …

Systemic sclerosis (SSc), an autoimmune disease that is associated with a number of
genetic and environmental risk factors, is characterized by progressive fibrosis and …

Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible
fibrotic disease associated with respiratory failure. The disease remains idiopathic, but …

Endothelial-to-mesenchymal transition (EndMT) is the process wherein endothelial cells
lose their typical endothelial cell markers and functions and adopt a mesenchymal-like …

Therapeutic angiogenesis presents a potential approach for treating ischemic heart
diseases especially in patients who are not appropriate candidates for traditional …