Motivation deficits, such as apathy, are pervasive in both neurological and psychiatric
diseases. Even when they are not the core symptom, they reduce quality of life, compromise …

Limited quantity and quality of interpersonal exchanges and relationships predict worse
symptomatic and hospitalization outcomes and limit functional recovery in people with …

Motivational impairment is a common feature of both depression and psychosis; however,
the psychological and neural mechanisms that give rise to motivational impairment in these …

Negative symptoms of schizophrenia are debilitating and chronic in nature, are difficult to
treat, and contribute to poor functional outcomes. Motivational deficits are a core negative …

Schizophrenia is associated with amotivation and reduced goal-directed behavior, which
have been linked to poor functional outcomes. Motivational deficits in schizophrenia are …

Highlights•Motivational deficits in schizophrenia may arise, in part, due to reduced
effort.•Studies show striatal and cingulate activation are associated with effort deficits.•Future …

Background Anhedonia is a cardinal feature of major depression and is hypothesized to be
driven by low motivation, in particular blunted reward sensitivity. It has been suggested to be …

Recent research suggests that schizophrenia is associated with reduced effort allocation.
We examined the willingness to expend effort, neural correlates of effort allocation, and the …

Objectives Deficits in anticipating pleasure may be an important dimension of anhedonia
and functioning in psychiatric disorders, particularly schizophrenia and depression; …

Abstract Purpose of Review Anhedonia, traditionally defined as a diminished capacity to
experience pleasure, has long been considered a core symptom of schizophrenia. However …