Extracellular matrix: functions in the nervous system
An astonishing number of extracellular matrix glycoproteins are expressed in dynamic
patterns in the develo** and adult nervous system. Neural stem cells, neurons, and glia …
patterns in the develo** and adult nervous system. Neural stem cells, neurons, and glia …
Tenascin-C: form versus function
SP Giblin, KS Midwood - Cell adhesion & migration, 2015 - Taylor & Francis
Tenascin-C is a large, multimodular, extracellular matrix glycoprotein that exhibits a very
restricted pattern of expression but an enormously diverse range of functions. Here, we …
restricted pattern of expression but an enormously diverse range of functions. Here, we …
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro
model to recapitulate human brain development and neurological diseases. However, the …
model to recapitulate human brain development and neurological diseases. However, the …
[HTML][HTML] Pax6 controls radial glia differentiation in the cerebral cortex
M Götz, A Stoykova, P Gruss - Neuron, 1998 - cell.com
Radial glia cells perform a dual function in the develo** nervous system as precursor cells
and guides for migrating neurons. We show here that during forebrain neurogenesis, the …
and guides for migrating neurons. We show here that during forebrain neurogenesis, the …
Neural bHLH genes control the neuronal versus glial fate decision in cortical progenitors
We have addressed the role of the proneural bHLH genes Neurogenin2 (Ngn2) and Mash1
in the selection of neuronal and glial fates by neural stem cells. We show that mice mutant …
in the selection of neuronal and glial fates by neural stem cells. We show that mice mutant …
β1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex
D Graus-Porta, S Blaess, M Senften… - Neuron, 2001 - cell.com
Mice that lack all β1-class integrins in neurons and glia die prematurely after birth with
severe brain malformations. Cortical hemispheres and cerebellar folia fuse, and cortical …
severe brain malformations. Cortical hemispheres and cerebellar folia fuse, and cortical …
KCNQ2 is a nodal K+ channel
Mutations in the gene encoding the K+ channel KCNQ2 cause neonatal epilepsy and
myokymia, indicating that KCNQ2 regulates the excitability of CNS neurons and motor …
myokymia, indicating that KCNQ2 regulates the excitability of CNS neurons and motor …
Neural stem cell differentiation into mature neurons: mechanisms of regulation and biotechnological applications
MS Vieira, AK Santos, R Vasconcellos… - Biotechnology …, 2018 - Elsevier
The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …
possibilities of applications in cell-based therapies such as tissue recomposition in …
Mice develop normally without tenascin.
Y Saga, T Yagi, Y Ikawa, T Sakakura… - Genes & …, 1992 - genesdev.cshlp.org
Tenascin, an extracellular matrix protein, is expressed in an unusually restricted pattern
during embryogenesis and has been implicated in a variety of morphogenetic phenomena …
during embryogenesis and has been implicated in a variety of morphogenetic phenomena …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …