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The complex aetiology of cerebral palsy
Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …
Consequently, CP is a public health priority for prevention, but its aetiology has proved …
Dysmaturation of premature brain: importance, cellular mechanisms, and potential interventions
JJ Volpe - Pediatric neurology, 2019 - Elsevier
Prematurity, especially preterm birth (less than 32 weeks' gestation), is common and
associated with high rates of both survival and neurodevelopmental disability, especially …
associated with high rates of both survival and neurodevelopmental disability, especially …
Preterm brain injury, antenatal triggers, and therapeutics: timing is key
DRMG Ophelders, R Gussenhoven, L Klein… - Cells, 2020 - mdpi.com
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …
[HTML][HTML] Early breast milk exposure modifies brain connectivity in preterm infants
Preterm infants are at increased risk of alterations in brain structure and connectivity, and
subsequent neurocognitive impairment. Breast milk may be more advantageous than …
subsequent neurocognitive impairment. Breast milk may be more advantageous than …
Neuroimaging of the preterm brain: review and recommendations
TE Inder, LS de Vries, DM Ferriero, PE Grant… - The Journal of …, 2021 - jpeds.com
The American Academy of Pediatrics'(AAP) recommendations for “Routine neuroimaging of
the preterm brain” focuses on cranial ultrasound (cUS) screening, initially for the diagnosis …
the preterm brain” focuses on cranial ultrasound (cUS) screening, initially for the diagnosis …
Microglial phagocytosis of neurons: diminishing neuronal loss in traumatic, infectious, inflammatory, and autoimmune CNS disorders
SF Yanuck - Frontiers in psychiatry, 2019 - frontiersin.org
Errors in neuron-microglial interaction are known to lead to microglial phagocytosis of live
neurons and excessive neuronal loss, potentially yielding poorer clinical outcomes. Factors …
neurons and excessive neuronal loss, potentially yielding poorer clinical outcomes. Factors …
[HTML][HTML] Microbiome-gut-brain axis in brain development, cognition and behavior during infancy and early childhood
The gut microbiota is increasingly recognized as a modulator of brain and behavior but its
role in early childhood, when the microbiome and the brain are both undergoing rapid …
role in early childhood, when the microbiome and the brain are both undergoing rapid …
[HTML][HTML] Neurodevelopmental outcomes following intrauterine growth restriction and very preterm birth
Objectives To evaluate whether intrauterine growth restriction (IUGR) adds further
neurodevelopmental risk to that posed by very preterm birth alone in terms of alterations in …
neurodevelopmental risk to that posed by very preterm birth alone in terms of alterations in …
Neurodevelopmental impairment in necrotising enterocolitis survivors: systematic review and meta-analysis
A Matei, L Montalva, A Goodbaum, G Lauriti… - Archives of Disease in …, 2020 - fn.bmj.com
Aim To determine (1) the incidence of neurodevelopmental impairment (NDI) in necrotising
enterocolitis (NEC),(2) the impact of NEC severity on NDI in these babies and (3) the …
enterocolitis (NEC),(2) the impact of NEC severity on NDI in these babies and (3) the …
[HTML][HTML] Maternal prenatal stress is associated with altered uncinate fasciculus microstructure in premature neonates
Background Maternal prenatal stress exposure (PNSE) increases risk for adverse
psychiatric and behavioral outcomes in offspring. The biological basis for this elevated risk is …
psychiatric and behavioral outcomes in offspring. The biological basis for this elevated risk is …