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Data-driven modelling of neurodegenerative disease progression: thinking outside the black box
Data-driven disease progression models are an emerging set of computational tools that
reconstruct disease timelines for long-term chronic diseases, providing unique insights into …
reconstruct disease timelines for long-term chronic diseases, providing unique insights into …
An update on genetic frontotemporal dementia
CV Greaves, JD Rohrer - Journal of neurology, 2019 - Springer
Frontotemporal dementia (FTD) is a highly heritable group of neurodegenerative disorders,
with around 30% of patients having a strong family history. The majority of that heritability is …
with around 30% of patients having a strong family history. The majority of that heritability is …
Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders
The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-
onset dementia. The diagnosis of bvFTD remains challenging because of the limited …
onset dementia. The diagnosis of bvFTD remains challenging because of the limited …
Frontotemporal dementia, where do we stand? A narrative review
Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …
Amyotrophic lateral sclerosis-frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria
This article presents the revised consensus criteria for the diagnosis of frontotemporal
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference
The heterogeneity of neurodegenerative diseases is a key confound to disease
understanding and treatment development, as study cohorts typically include multiple …
understanding and treatment development, as study cohorts typically include multiple …
Imaging biomarkers in neurodegeneration: current and future practices
There is an increasing role for biological markers (biomarkers) in the understanding and
diagnosis of neurodegenerative disorders. The application of imaging biomarkers …
diagnosis of neurodegenerative disorders. The application of imaging biomarkers …
Serum neurofilament light chain protein is a measure of disease intensity in frontotemporal dementia
Objective: To investigate serum neurofilament light chain (NfL) concentrations in
frontotemporal dementia (FTD) and to see whether they are associated with the severity of …
frontotemporal dementia (FTD) and to see whether they are associated with the severity of …
Neuroinflammation in frontotemporal dementia
Frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative
disorders with different pathological signatures, genetic variability and complex disease …
disorders with different pathological signatures, genetic variability and complex disease …
Diagnostic contribution and therapeutic perspectives of transcranial magnetic stimulation in dementia
Transcranial magnetic stimulation (TMS) is a powerful tool to probe in vivo brain circuits, as it
allows to assess several cortical properties such as excitability, plasticity and connectivity in …
allows to assess several cortical properties such as excitability, plasticity and connectivity in …